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1/18/2025 8:12:09 AM | Browse: 40 | Download: 96
Publication Name World Journal of Gastrointestinal Oncology
Manuscript ID 101888
Country United States
Received
2024-09-29 18:27
Peer-Review Started
2024-09-29 18:27
To Make the First Decision
Return for Revision
2024-10-30 07:59
Revised
2024-11-07 17:25
Second Decision
2024-12-02 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2024-12-02 08:09
Articles in Press
2024-12-02 08:09
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2024-12-17 09:09
Publish the Manuscript Online
2025-01-18 08:12
ISSN 1948-5204 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Letter to the Editor
Article Title Radiotherapy dosage: A neural network approach for uninvolved liver dose in stereotactic body radiation therapy for liver cancer
Manuscript Source Invited Manuscript
All Author List Arunkumar Krishnan
ORCID
Author(s) ORCID Number
Arunkumar Krishnan http://orcid.org/0000-0002-9452-7377
Funding Agency and Grant Number
Corresponding Author Arunkumar Krishnan, MD, MS, Assistant Professor, Research Scientist, Department of Supportive Oncology, Atrium Health Levine Cancer, 1021 Morehead Medical Drive, Suite 70100, Charlotte, NC 28204, United States. dr.arunkumar.krishnan@gmail.com
Key Words Liver cancer; Radiotherapy dosage; Dose prediction; Machine learning; Stereotactic body radiotherapy
Core Tip A study by Zhang et al developed a neural network-based predictive model for estimating doses to uninvolved liver tissue during stereotactic body radiation therapy (RT), representing a significant advancement in personalizing RT for liver cancer patients. The model demonstrated high predictive accuracy, with R-values exceeding 0.8, highlighting its potential to standardize dose estimation and improve patient safety by reducing biases. The study's relatively small patient cohort (114 patients) raises concerns about selection bias and limits the model's generalizability. Future research should involve larger multicenter cohorts and a more comprehensive cohort of patient characteristics to improve the generalizability of models and clinical relevance. Interdisciplinary collaboration among oncologists, data scientists, and radiation technologists is vital for improving predictive models and the efficacy and precision of cancer treatment.
Publish Date 2025-01-18 08:12
Citation <p>Krishnan A. Radiotherapy dosage: A neural network approach for uninvolved liver dose in stereotactic body radiation therapy for liver cancer. <i>World J Gastrointest Oncol</i> 2025; 17(2): 101888</p>
URL https://www.wjgnet.com/1948-5204/full/v17/i2/101888.htm
DOI https://dx.doi.org/10.4251/wjgo.v17.i2.101888
Full Article (PDF) WJGO-17-101888-with-cover.pdf
Manuscript File 101888_Auto_Edited_014319.docx
Answering Reviewers 101888-answering-reviewers.pdf
Audio Core Tip 101888-audio.mp3
Conflict-of-Interest Disclosure Form 101888-conflict-of-interest-statement.pdf
Copyright License Agreement 101888-copyright-assignment.pdf
Peer-review Report 101888-peer-reviews.pdf
Scientific Misconduct Check 101888-scientific-misconduct-check.png
Scientific Editor Work List 101888-scientific-editor-work-list.pdf
CrossCheck Report 101888-crosscheck-report.png
CrossCheck Report 101888-crosscheck-report.pdf