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Articles Published Processes
6/23/2025 7:18:41 AM | Browse: 155 | Download: 769
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Received |
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2024-10-08 00:16 |
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Peer-Review Started |
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2024-10-18 00:48 |
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First Decision by Editorial Office Director |
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2025-01-08 13:55 |
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Return for Revision |
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2025-01-08 13:55 |
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Revised |
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2025-01-26 16:14 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-02-20 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-02-20 09:10 |
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Articles in Press |
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2025-02-20 09:10 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-01 01:20 |
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Publish the Manuscript Online |
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2025-06-23 07:18 |
| ISSN |
2220-3249 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biochemistry & Molecular Biology |
| Manuscript Type |
Observational Study |
| Article Title |
Micro RNAs as a potential biomarker for predicting liver fibrosis severity in hepatitis C virus affected patients
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Navneet Kaur, Ravinder Garg, Chaitanya Tapasvi and Gitanjali Goyal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Navneet Kaur, Department of Biochemistry, Guru Gobind Singh Medical College and Hospital, Baba Farid University of Health Sciences, Sadiq Road, Faridkot 151203, Punjab, India. navmann23@yahoo.com |
| Key Words |
Hepatitis C virus; Non-invasive biomarkers; MicroRNAs; Complex bayesian networks; Liver fibrosis; Liver diseases |
| Core Tip |
Early liver fibrosis detection by biomarkers improves treatment and prevents cirrhosis and liver failure. We investigated various microRNAs (miRNA-122, miRNA-21, miRNA-199, miRNA-155) to determine liver fibrosis severity in untreated Hepatitis C virus (HCV) patients. Our study examined how miRNAs affect HCV fibrosis diagnosis. We tested miRNAs for liver fibrosis stage using statistical and probabilistic approaches for 100 HCV-positive individuals. Bayesian Networks were used to develop a miRNA diagnostic relationship for HCV liver fibrosis severity. miR-122, miR-155, and miR-21 were significantly elevated relative to controls and fibrosis severity (P ≤ 0.05) whereas MiR-199a decreased with fibrosis. Diagnostically, miR-122, miR-155, and miR-21 are accurate fibrosis biomarkers. |
| Publish Date |
2025-06-23 07:18 |
| Citation |
Kaur N, Garg R, Tapasvi C, Goyal G. Micro RNAs as a potential biomarker for predicting liver fibrosis severity in hepatitis C virus affected patients. World J Virol 2025; 14(2): 101976 |
| URL |
https://www.wjgnet.com/2220-3249/full/v14/i2/101976.htm |
| DOI |
https://dx.doi.org/10.5501/wjv.v14.i2.101976 |
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