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Articles Published Processes
2/28/2025 10:47:28 AM | Browse: 171 | Download: 601
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Received |
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2024-10-14 05:44 |
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Peer-Review Started |
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2024-10-16 00:48 |
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First Decision by Editorial Office Director |
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2024-12-09 05:45 |
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Return for Revision |
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2024-12-09 05:45 |
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Revised |
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2025-01-04 15:25 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-02-10 02:33 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-02-10 06:49 |
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Articles in Press |
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2025-02-10 06:49 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-02-21 01:55 |
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Publish the Manuscript Online |
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2025-02-28 10:47 |
| ISSN |
1948-9358 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cell Biology |
| Manuscript Type |
Editorial |
| Article Title |
Exploring a novel mechanism for targeting β-arrestin-2 in the management of diabetic nephropathy
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Na Liu, Wei-Tao Yan and Kun Xiong |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82303047, 82372507, 82172196 and 32401046 |
| Natural Science Foundation of Hunan Province |
2022JJ40801 |
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| Corresponding Author |
Kun Xiong, PhD, Professor, Department of Anatomy and Neurobiology, School of Basic Medical Science, Central South University, No. 172 Tongzipo Road, Changsha 410013, Hunan Province, China. xiongkun2001@163.com |
| Key Words |
Diabetes mellitus; Diabetic nephropathy; β-arrestin-2; Endoplasmic reticulum stress; ATF6 signaling pathway |
| Core Tip |
Diabetic nephropathy (DN), a complication of diabetes mellitus, poses significant challenges in the management. Liu et al observed that β-arrestin-2 deteriorates DN through inducing endoplasmic reticulum (ER) stress, and inhibiting β-arrestin-2 may protect glomerular endothelial cells and mitigate DN progression by curbing ER stress. This research underscores the significance of ER stress in DN and reveals an innovative molecular pathway involving β-arrestin-2 that may contribute to DN progression, offering potential targets for therapeutic interventions. Nevertheless, further clinical validation and investigation are necessary to confirm the clinical application of these findings. |
| Publish Date |
2025-02-28 10:47 |
| Citation |
Liu N, Yan WT, Xiong K. Exploring a novel mechanism for targeting β-arrestin-2 in the management of diabetic nephropathy. World J Diabetes 2025; 16(4): 101994 |
| URL |
https://www.wjgnet.com/1948-9358/full/v16/i4/101994.htm |
| DOI |
https://dx.doi.org/10.4239/wjd.v16.i4.101994 |
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