Publication Name	World Journal of Gastroenterology
Manuscript ID	102007
Country	China

Received	2024-10-05 14:32
Peer-Review Started	2024-10-05 14:32
To Make the First Decision
Return for Revision	2025-01-18 01:37
Revised	2025-01-23 01:49
Second Decision	2025-02-26 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-26 05:32
Articles in Press	2025-02-26 05:32
Publication Fee Transferred	2025-01-24 13:47
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-14 02:13
Publish the Manuscript Online	2025-03-26 08:40

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Transplantation
Manuscript Type	Meta-Analysis
Article Title	Liver transplantation improves prognosis across all grades of acute-on-chronic liver failure patients: A systematic review and meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Zhi-Xin Li, Jun-Hao Zeng, Hong-Lin Zhong and Bo Peng
ORCID	Author(s) ORCID Number Zhi-Xin Li http://orcid.org/0000-0003-3608-2266 Jun-Hao Zeng http://orcid.org/0009-0006-4988-4259 Hong-Lin Zhong http://orcid.org/0009-0006-0828-2112 Bo Peng http://orcid.org/0000-0003-4482-2885
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 82300857
Corresponding Author	Bo Peng, MD, The Transplantation Center, The Third Xiangya Hospital, Central South University, No. 138 Tongzipo Road, Yuelu District, Changsha 410013, Hunan Province, China. pengbo_2000@163.com
Key Words	Acute-on-chronic liver failure; Liver transplantation; Postoperative prognosis; Survival rate; Infection; Meta-analysis
Core Tip	Given the challenges associated with liver transplantation (LT) in the treatment of acute-on-chronic liver failure (ACLF), it is crucial to evaluate patient prognosis across different ACLF grades following LT. This meta-analysis revealed that ACLF-1 and ACLF-2 patients achieve favorable survival outcomes following LT. Although ACLF-3 patients exhibit relatively lower survival rates and higher infection rates, LT remains a promising option to improve their prognosis. To optimize the use of limited donor organs, further refinement of organ allocation and scoring systems is imperative. A comprehensive assessment of pre-transplant health status, concurrent organ failure, and donor characteristics should be performed before LT.
Publish Date	2025-03-26 08:40
Citation	<p>Li ZX, Zeng JH, Zhong HL, Peng B. Liver transplantation improves prognosis across all grades of acute-on-chronic liver failure patients: A systematic review and meta-analysis. <i>World J Gastroenterol</i> 2025; 31(12): 102007</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i12/102007.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i12.102007

Full Article (PDF)	WJG-31-102007-with-cover.pdf
PRISMA 2009 Checklist	102007-PRISMA-2009-Checklist.pdf
Manuscript File	102007_Auto_Edited_074924.docx
Answering Reviewers	102007-answering-reviewers.pdf
Audio Core Tip	102007-audio.mp3
Biostatistics Review Certificate	102007-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	102007-conflict-of-interest-statement.pdf
Copyright License Agreement	102007-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	102007-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	102007-non-native-speakers.pdf
Supplementary Material	102007-supplementary-material.pdf
Peer-review Report	102007-peer-reviews.pdf
Scientific Misconduct Check	102007-scientific-misconduct-check.png
Scientific Editor Work List	102007-scientific-editor-work-list.pdf
CrossCheck Report	102007-crosscheck-report.pdf