| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Review |
| Article Title |
Traditional Chinese medicine for chronic atrophic gastritis: Efficacy, mechanisms and targets
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Li Wang, Yan-Jie Lian, Jin-Sheng Dong, Ming-Kun Liu, Hong-Liang Liu, Zheng-Min Cao, Qing-Nan Wang, Wen-Liang Lyu and Yu-Ning Bai |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences |
CI2021A00806 |
| High Level Chinese Medical Hospital Promotion Project |
HLCMHPP2023086 |
| Fundamental Research Funds for the Central Public Welfare Research Institutes |
ZZ17-XRZ-041 |
|
| Corresponding Author |
Yu-Ning Bai, Department of Digestive, Guang’anmen Hospital, China Academy of Chinese Medical Sciences, No. 5 Beixiange, Xicheng District, Beijing 100053, China. byn-1973@163.com |
| Key Words |
Traditional Chinese medicine; Herbal medicine; Chronic atrophic gastritis; Therapeutic efficacy; Molecular target |
| Core Tip |
Traditional Chinese medicine (TCM) exerts a protective influence on chronic atrophic gastritis through multiple mechanisms, such as enhancing the gastric mucosal “mucus-bicarbonate” barrier, regulating cell proliferation and apoptosis, ameliorating microcirculation, modulating immune responses, and influencing intestinal microecology. Specific TCM compounds and monomers, for instance, berberine, morroniside, and notoginsenoside R1, exhibit therapeutic potential by targeting inflammation, oxidative stress, and gastric mucosal defense. It is evident that TCM is a potential treatment. Nevertheless, the standardization of TCM research and clinical practices is indispensable for optimizing the management of chronic atrophic gastritis. |
| Publish Date |
2025-02-18 09:00 |
| Citation |
<p>Wang L, Lian YJ, Dong JS, Liu MK, Liu HL, Cao ZM, Wang QN, Lyu WL, Bai YN. Traditional Chinese medicine for chronic atrophic gastritis: Efficacy, mechanisms and targets. <i>World J Gastroenterol</i> 2025; 31(9): 102053</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i9/102053.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i9.102053 |
