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Articles Published Processes
1/13/2025 8:26:45 AM | Browse: 26 | Download: 85
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Received |
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2024-10-09 08:01 |
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Peer-Review Started |
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2024-10-09 08:01 |
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To Make the First Decision |
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Return for Revision |
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2024-12-12 07:50 |
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2024-12-12 10:14 |
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Second Decision |
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2024-12-19 02:36 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2024-12-19 08:50 |
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Articles in Press |
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2024-12-19 08:50 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2024-12-23 01:21 |
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Typeset the Manuscript |
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2024-12-31 01:13 |
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Publish the Manuscript Online |
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2025-01-13 08:26 |
| ISSN |
2218-5836 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Orthopedics |
| Manuscript Type |
Editorial |
| Article Title |
Fundamentals of intervertebral disc degeneration and related discogenic pain
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Bao-Gan Peng |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bao-Gan Peng, Chief Physician, MD, PhD, Professor, Department of Orthopaedics, The Third Medical Center, General Hospital of the Chinese People’s Liberation Army, No. 69 Yongding Road, Beijing 100039, China. pengbaogan@163.com |
| Key Words |
Intervertebral disc degeneration; Discogenic low back pain; Neurogenic inflammation; Neuropeptides; Substance P; Calcitonin gene-related peptide |
| Core Tip |
Animal models, histological and biomechanical studies have shown that annular tear or endplate injury is the initiating factor for painful disc degeneration. Neurogenic inflammation of the disc refers to the release of neuropeptides such as SP and CGRP from the nociceptive nerves that innervate the disc in response to disc injury, leading to progressive disc degeneration and discogenic pain. |
| Publish Date |
2025-01-13 08:26 |
| Citation |
<p>Peng BG. Fundamentals of intervertebral disc degeneration and related discogenic pain. <i>World J Orthop</i> 2025; 16(1): 102119</p> |
| URL |
https://www.wjgnet.com/2218-5836/full/v16/i1/102119.htm |
| DOI |
https://dx.doi.org/10.5312/wjo.v16.i1.102119 |
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