Publication Name	World Journal of Gastroenterology
Manuscript ID	102135
Country	China

Received	2024-10-09 13:00
Peer-Review Started	2024-10-09 13:00
To Make the First Decision
Return for Revision	2024-11-26 03:26
Revised	2024-12-02 05:00
Second Decision	2024-12-17 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-17 07:03
Articles in Press	2024-12-17 07:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2024-12-18 06:00
Publish the Manuscript Online	2024-12-30 06:47

ISSN	1007-9327 (print) and 2219-2840 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Case Report
Article Title	Mild liver injury following withdrawal of long-term prednisone therapy: A case report
Manuscript Source	Unsolicited Manuscript
All Author List	Jing-Wen Zhu, Jun Yan, Zhi-Han Zhang and Tian-Qi Wang
ORCID	Author(s) ORCID Number Tian-Qi Wang http://orcid.org/0009-0001-2719-359X
Funding Agency and Grant Number
Corresponding Author	Tian-Qi Wang, Assistant Professor, PhD, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Zhengzhou University, No. 100 Kexue Avenue, Zhengzhou 450001, Henan Province, China. tianqi@zzu.edu.cn
Key Words	Liver injury; Transaminase; Prednisone; Addison's disease; Adrenal insufficiency; Case report
Core Tip	This paper describes a rare case of mild hypertransaminasemia occurring following withdrawal of long-term prednisone therapy, a condition that is potentially underestimated and easily ignored. The presented case suggests that hypertransaminasemia caused by glucocorticoid withdrawal may have different features from hypertransaminasemia due to primary Addison's disease; the severity of adrenal insufficiency may be associated with the development of elevated transminases and their levels; and glycyrrhizin may be an option for patients with mild adrenal insufficiency due to glucocorticoid withdrawal who have planned to discontinue this hormonal therapy.
Publish Date	2024-12-30 06:47
Citation	<p>Zhu JW, Yan J, Zhang ZH, Wang TQ. Mild liver injury following withdrawal of long-term prednisone therapy: A case report. <i>World J Gastroenterol</i> 2025; 31(4): 102135</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i4/102135.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i4.102135

Full Article (PDF)	WJG-31-102135-with-cover.pdf
CARE Checklist–2016	102135-CARE-Checklist-2016.pdf
Manuscript File	102135_Auto_Edited_080511.docx
Answering Reviewers	102135-answering-reviewers.pdf
Audio Core Tip	102135-audio.m4a
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Peer-review Report	102135-peer-reviews.pdf
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Scientific Editor Work List	102135-scientific-editor-work-list.pdf
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CrossCheck Report	102135-crosscheck-report.pdf