| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Study |
| Article Title |
Extended travel for donor organs: Is cold static storage still relevant
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Montana Reynolds, Martin Gerard Walsh, Ervin Y Cui, Divyaam Satija, Doug A Gouchoe, Matthew C Henn, Kukbin Choi, Nahush A Mokadam, Asvin M Ganapathi and Bryan A Whitson |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| The Jewel and Frank Benson Family Endowment |
|
| The Jewel and Frank Benson Research Professorship |
|
|
| Corresponding Author |
Bryan A Whitson, MD, PhD, Professor, Division of Cardiac Surgery, Department of Surgery, The Ohio State University Wexner Medical Center, N-816 Doan Hall, 410 W 10th Avenue, Columbus, OH 43201, United States. bryan.whitson@osumc.edu |
| Key Words |
Normothermic perfusion; Cold static storage; United Network for Organ Sharing; Machine perfusion; Ischemic time; Ex vivo lung perfusion; Transplantation lung |
| Core Tip |
This study investigates the effectiveness of cold static storage (CSS) vs ex vivo lung perfusion (EVLP) for donor lungs transported over 750 nautical miles. Midterm survival outcomes were similar but recipients in the EVLP group experienced significantly higher perioperative morbidity, including post-operative dialysis and ventilator use. If ischemic times remain less than 8 hours, CSS remains likely a viable option for extended travel, especially in resource-limited settings. This research provides important insights for transplant centers seeking to optimize organ preservation strategies for long-distance donor retrieval. |
| Publish Date |
2025-04-18 08:22 |
| Citation |
<p>Reynolds M, Walsh MG, Cui EY, Satija D, Gouchoe DA, Henn MC, Choi K, Mokadam NA, Ganapathi AM, Whitson BA. Extended travel for donor organs: Is cold static storage still relevant. <i>World J Transplant</i> 2025; 15(3): 102150</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i3/102150.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i3.102150 |
