Publication Name	World Journal of Gastrointestinal Surgery
Manuscript ID	102261
Country	China

Received	2024-10-13 11:07
Peer-Review Started	2024-10-13 11:07
To Make the First Decision
Return for Revision	2024-11-26 08:41
Revised	2024-12-05 03:15
Second Decision	2024-12-16 02:46
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-16 06:36
Articles in Press	2024-12-16 06:36
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-06 08:45
Publish the Manuscript Online	2025-01-22 09:25

ISSN	1948-9366 (online)
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Category	Oncology
Manuscript Type	Letter to the Editor
Article Title	Harnessing the prognostic power of preoperative systemic immune-inflammation index/albumin ratio in hepatocellular carcinoma resection
Manuscript Source	Invited Manuscript
All Author List	Zhao-Nan Zhang, Liang Hao, Shuang Han, Shan-Shan Li, Si-Xiang Lin and Yan-Dong Miao
ORCID	Author(s) ORCID Number Liang Hao http://orcid.org/0009-0001-4786-3378 Yan-Dong Miao http://orcid.org/0000-0002-1429-8915
Funding Agency and Grant Number	Funding Agency Grant Number Shandong Province Medical and Health Science and Technology Development Plan Project 202203030713 Science and Technology Program of Yantai Affiliated Hospital of Binzhou Medical University YTFY2022KYQD06
Corresponding Author	Yan-Dong Miao, Cancer Center, Yantai Affiliated Hospital of Binzhou Medical University,The 2nd Medical College of Binzhou Medical University, No. 717 Jinbu Street, Muping District, Yantai 264100, Shandong Province, China. miaoyd_22@bzmc.edu.cn
Key Words	Hepatocellular carcinoma; Hepatocellular carcinoma; Inflammation; hepatocellular carcinoma resection
Core Tip	The study highlights the significance of the preoperative systemic immune-inflammation index/albumin (SII/ALB) ratio as an independent prognostic indicator for hepatocellular carcinoma patients undergoing curative resection. The SII/ALB ratio integrates inflammatory and nutritional biomarkers, providing a cost-effective and accessible tool for predicting overall and recurrence-free survival. Additionally, a predictive nomogram incorporating SII/ALB with clinical parameters improves patient stratification, guiding surgical decisions and postoperative care. While promising, further multi-center validation across diverse patient populations is needed to confirm its broad clinical applicability. Moreover, dynamic monitoring of SII/ALB throughout treatment could enhance personalized therapy, making it a valuable asset even in resource-limited healthcare settings.
Publish Date	2025-01-22 09:25
Citation	<p>Zhang ZN, Hao L, Han S, Li SS, Lin SX, Miao YD. Harnessing the prognostic power of preoperative systemic immune-inflammation index/albumin ratio in hepatocellular carcinoma resection. <i>World J Gastrointest Surg</i> 2025; 17(2): 102261</p>
URL	https://www.wjgnet.com/1948-9366/full/v17/i2/102261.htm
DOI	https://dx.doi.org/10.4240/wjgs.v17.i2.102261

Full Article (PDF)	WJGS-17-102261-with-cover.pdf
Manuscript File	102261_Auto_Edited_031527.docx
Answering Reviewers	102261-answering-reviewers.pdf
Audio Core Tip	102261-audio.m4a
Conflict-of-Interest Disclosure Form	102261-conflict-of-interest-statement.pdf
Copyright License Agreement	102261-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	102261-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	102261-non-native-speakers.pdf
Peer-review Report	102261-peer-reviews.pdf
Scientific Misconduct Check	102261-scientific-misconduct-check.png
Scientific Editor Work List	102261-scientific-editor-work-list.pdf
CrossCheck Report	102261-crosscheck-report.pdf