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Articles Published Processes
3/26/2025 4:06:55 AM | Browse: 12 | Download: 40
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Received |
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2024-10-13 18:42 |
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Peer-Review Started |
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2024-10-13 18:42 |
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To Make the First Decision |
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Return for Revision |
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2025-02-08 13:25 |
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Revised |
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2025-02-20 18:24 |
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Second Decision |
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2025-03-05 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-05 10:43 |
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Articles in Press |
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2025-03-05 10:43 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-03-07 02:31 |
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Typeset the Manuscript |
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2025-03-18 09:34 |
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Publish the Manuscript Online |
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2025-03-26 04:06 |
| ISSN |
1948-5182 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Metabolic dysfunction-associated steatotic liver disease and omega-6 polyunsaturated fatty acids: Friends or foes
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Mona A Hegazy, Safaa M Ahmed, Shaimaa M Sultan, Osama F Afifi, Manal A Mohamed, Alshimaa E Azab, Mohamed A Hassanen and Rakan K Zaben |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Mona A Hegazy, MD, Professor, Department of Internal Medicine, Kasr Aliny Hospital, Faculty of Medicine, Cairo University, Kasr Alainy Street, Garden City, Cairo 12556, Egypt. monahegazy@cu.edu.eg |
| Key Words |
Eicosanoids; Steatohepatitis; Oxidative stress; Lipid metabolism; Arachidonic acid; Conjugated linoleic acid; Omega-6 polyunsaturated fatty acids; Metabolic dysfunction-associated steatotic liver disease |
| Core Tip |
Dietary habits extended beyond influencing metabolic dysfunction-associated steatotic liver disease onset, serving as a fundamental component in its therapeutic management. While fats have a deleterious role in the pathogenesis of liver steatosis and fibrosis, unsaturated fats provide a crucial safeguard in metabolic dysfunction-associated steatotic liver disease management. Given that omega-6 polyunsaturated fat subtypes exhibit varying pro- and anti-inflammatory effects, most arachidonic acid-derived eicosanoids, exhibit pro-inflammatory effects on the same time linoleic acid and natural conjugated linoleic acid do not increase inflammation, even at high doses, and may even exert beneficial effects. Therefore, further research is needed to explore dietary sources of healthy omega-6 fatty acids. |
| Publish Date |
2025-03-26 04:06 |
| Citation |
<p>Hegazy MA, Ahmed SM, Sultan SM, Afifi OF, Mohamed MA, Azab AE, Hassanen MA, Zaben RK. Metabolic dysfunction-associated steatotic liver disease and omega-6 polyunsaturated fatty acids: Friends or foes. <i>World J Hepatol</i> 2025; 17(3): 102286</p> |
| URL |
https://www.wjgnet.com/1948-5182/full/v17/i3/102286.htm |
| DOI |
https://dx.doi.org/10.4254/wjh.v17.i3.102286 |
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