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4/18/2025 8:22:02 AM | Browse: 15 | Download: 36
Publication Name World Journal of Transplantation
Manuscript ID 102287
Country Latvia
Received
2024-10-13 20:45
Peer-Review Started
2024-10-13 20:45
To Make the First Decision
Return for Revision
2025-01-20 07:42
Revised
2025-01-31 15:28
Second Decision
2025-02-20 02:38
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-20 09:58
Articles in Press
2025-02-20 09:58
Publication Fee Transferred
2025-02-12 09:53
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-03-03 03:47
Publish the Manuscript Online
2025-04-18 08:22
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Major adverse cardiovascular events and hyperuricemia as an effect-modifying factor in kidney transplant recipients
Manuscript Source Unsolicited Manuscript
All Author List Elizabete Junk, Lilian Tzivian, Inese Folkmane, Kristofs Folkmanis, Janis Jushinskis, Gunta Strazda, Valdis Folkmanis, Viktorija Kuzema and Aivars Petersons
ORCID
Author(s) ORCID Number
Inese Folkmane http://orcid.org/0009-0005-7231-9517
Valdis Folkmanis http://orcid.org/0009-0000-3493-9137
Funding Agency and Grant Number
Corresponding Author Inese Folkmane, MD, PhD, Professor, Centre of Nephrology, Pauls Stradiņš Clinical University Hospital, Pilsoņu 13, Riga LV-1002, Latvia. folkmane.inese@inbox.lv
Key Words Kidney transplantation; Hyperuricemia; Uric acid; Cardiovascular risk; Major adverse cardiovascular events; Effect modification by hyperuricemia; Hyperuricemia treatment
Core Tip The relationship between hyperuricemia (HU) and major adverse cardiovascular (CV) events (MACEs) after kidney transplantation (KT) remains a topic of contention. We investigated the association between potential CV risk factors related to KT and MACEs, and their potential modification by HU. A very high level (> 475 μmol/L) of uric acid was found to act as an effect-modifying factor for MACEs, especially when combined with other risk factors such as previous CV events and anemia. This study makes an innovative contribution to the field by demonstrating the role of HU as a modulating factor on MACEs after KT.
Publish Date 2025-04-18 08:22
Citation <p>Junk E, Tzivian L, Folkmane I, Folkmanis K, Jushinskis J, Strazda G, Folkmanis V, Kuzema V, Petersons A. Major adverse cardiovascular events and hyperuricemia as an effect-modifying factor in kidney transplant recipients. <i>World J Transplant</i> 2025; 15(3): 102287</p>
URL https://www.wjgnet.com/2220-3230/full/v15/i3/102287.htm
DOI https://dx.doi.org/10.5500/wjt.v15.i3.102287
Full Article (PDF) WJT-15-102287-with-cover.pdf
STROBE Statement 102287-STROBE-statement.pdf
Manuscript File 102287_Auto_Edited_030215.docx
Answering Reviewers 102287-answering-reviewers.pdf
Audio Core Tip 102287-audio.mp3
Biostatistics Review Certificate 102287-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 102287-conflict-of-interest-statement.pdf
Copyright License Agreement 102287-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 102287-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 102287-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 102287-non-native-speakers.pdf
Peer-review Report 102287-peer-reviews.pdf
Scientific Misconduct Check 102287-scientific-misconduct-check.png
Scientific Editor Work List 102287-scientific-editor-work-list.pdf
CrossCheck Report 102287-crosscheck-report.pdf