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3/26/2025 10:16:45 AM | Browse: 25 | Download: 47
Publication Name World Journal of Clinical Oncology
Manuscript ID 102297
Country China
Received
2024-10-14 09:14
Peer-Review Started
2024-10-14 09:14
To Make the First Decision
Return for Revision
2024-11-28 09:40
Revised
2024-12-20 16:51
Second Decision
2025-02-27 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-27 08:44
Articles in Press
2025-02-27 08:44
Publication Fee Transferred
2024-12-27 14:17
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-03-13 08:30
Publish the Manuscript Online
2025-03-26 10:16
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Case Report
Article Title Combining anti-PD-1 antibodies with surufatinib for gastrointestinal neuroendocrine carcinoma: Two cases report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Lou-Lu Gao, Dong-Ni Gao, Hong-Tu Yuan, Wen-Qiang Chen, Jing Yang and Jie-Qiong Peng
ORCID
Author(s) ORCID Number
Wen-Qiang Chen http://orcid.org/0000-0002-0350-1383
Jie-Qiong Peng http://orcid.org/0000-0001-7724-7886
Funding Agency and Grant Number
Corresponding Author Jie-Qiong Peng, Department of Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, No. 440 Jiyan Road, Jinan 250117, Shandong Province, China. 15589116608@163.com
Key Words Gastrointestinal neuroendocrine carcinoma; Immune checkpoint inhibitors; Angiogenesis inhibitors; Combination therapy; Case report
Core Tip Effective treatment options for metastatic gastrointestinal neuroendocrine carcinomas (GI-NECs) are limited after chemotherapy failure. This study presents the cases of two patients with metastatic rectal and duodenal neuroendocrine carcinomas who achieved sustained remission and long-term survival through a combination of antiangiogenic targeted therapy and anti-PD-1 immunotherapy. These cases highlight the potential of this combination as a posterior-line treatment for GI-NECs, offering new insights into their management.
Publish Date 2025-03-26 10:16
Citation <p>Gao LL, Gao DN, Yuan HT, Chen WQ, Yang J, Peng JQ. Combining anti-PD-1 antibodies with surufatinib for gastrointestinal neuroendocrine carcinoma: Two cases report and review of literature. <i>World J Clin Oncol</i> 2025; 16(4): 102297</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i4/102297.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i4.102297
Full Article (PDF) WJCO-16-102297-with-cover.pdf
CARE Checklist–2016 102297-CARE-Checklist-2016.pdf
Manuscript File 102297_Auto_Edited_023633.docx
Answering Reviewers 102297-answering-reviewers.pdf
Audio Core Tip 102297-audio.m4a
Conflict-of-Interest Disclosure Form 102297-conflict-of-interest-statement.pdf
Copyright License Agreement 102297-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 102297-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 102297-non-native-speakers.pdf
Peer-review Report 102297-peer-reviews.pdf
Scientific Misconduct Check 102297-scientific-misconduct-check.png
Scientific Editor Work List 102297-scientific-editor-work-list.pdf
CrossCheck Report 102297-crosscheck-report.pdf