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Articles Published Processes
3/26/2025 10:16:45 AM | Browse: 25 | Download: 47
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Received |
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2024-10-14 09:14 |
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Peer-Review Started |
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2024-10-14 09:14 |
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To Make the First Decision |
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Return for Revision |
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2024-11-28 09:40 |
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Revised |
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2024-12-20 16:51 |
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Second Decision |
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2025-02-27 02:40 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-27 08:44 |
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Articles in Press |
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2025-02-27 08:44 |
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Publication Fee Transferred |
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2024-12-27 14:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-13 08:30 |
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Publish the Manuscript Online |
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2025-03-26 10:16 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Case Report |
Article Title |
Combining anti-PD-1 antibodies with surufatinib for gastrointestinal neuroendocrine carcinoma: Two cases report and review of literature
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Lou-Lu Gao, Dong-Ni Gao, Hong-Tu Yuan, Wen-Qiang Chen, Jing Yang and Jie-Qiong Peng |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Jie-Qiong Peng, Department of Oncology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, No. 440 Jiyan Road, Jinan 250117, Shandong Province, China. 15589116608@163.com |
Key Words |
Gastrointestinal neuroendocrine carcinoma; Immune checkpoint inhibitors; Angiogenesis inhibitors; Combination therapy; Case report |
Core Tip |
Effective treatment options for metastatic gastrointestinal neuroendocrine carcinomas (GI-NECs) are limited after chemotherapy failure. This study presents the cases of two patients with metastatic rectal and duodenal neuroendocrine carcinomas who achieved sustained remission and long-term survival through a combination of antiangiogenic targeted therapy and anti-PD-1 immunotherapy. These cases highlight the potential of this combination as a posterior-line treatment for GI-NECs, offering new insights into their management. |
Publish Date |
2025-03-26 10:16 |
Citation |
<p>Gao LL, Gao DN, Yuan HT, Chen WQ, Yang J, Peng JQ. Combining anti-PD-1 antibodies with surufatinib for gastrointestinal neuroendocrine carcinoma: Two cases report and review of literature. <i>World J Clin Oncol</i> 2025; 16(4): 102297</p> |
URL |
https://www.wjgnet.com/2218-4333/full/v16/i4/102297.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v16.i4.102297 |
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