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Articles Published Processes
6/16/2025 10:38:22 AM | Browse: 20 | Download: 223
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Received |
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2024-10-14 12:54 |
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Peer-Review Started |
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2024-10-14 12:54 |
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To Make the First Decision |
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Return for Revision |
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2025-03-05 07:42 |
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Revised |
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2025-03-07 14:56 |
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Second Decision |
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2025-03-27 02:39 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-03-27 07:24 |
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Articles in Press |
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2025-03-27 07:24 |
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Publication Fee Transferred |
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2025-03-19 04:59 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-06-06 08:01 |
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Publish the Manuscript Online |
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2025-06-16 10:38 |
| ISSN |
2219-2808 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Pediatrics |
| Manuscript Type |
Observational Study |
| Article Title |
Incidence of gastro-esophageal reflux disease in mechanically ventilated full-term Egyptian neonates by detection of pepsin in endotracheal aspirate
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Amira Elrefaee, Abdel-Rahman A Abdel-Razek, Zeinab S Abdelkhalek, Peter Samaan and Amir Fawzy Kamal |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Amir Fawzy Kamal, MD, Department of Pediatrics, Faculty of Medicine, Cairo University, Kasr Al-Aini Street, Cairo 11562, Egypt, Cairo 02, Al Qāhirah, Egypt. amirfawzy12314@gmail.com |
| Key Words |
Gastroesophageal reflux disease; Neonates; Mechanical ventilation; Pepsin; Endotracheal aspirates |
| Core Tip |
This study evaluates the incidence of gastroesophageal reflux disease (GERD) in mechanically ventilated full-term neonates using pepsin detection in endotracheal aspirates (ETA). Conducted on 97 neonates, the study demonstrates that pepsin was detected in 76.7% of samples collected, with significant correlations between pepsin levels, FiO2, feeding amount, and hospital stay duration. The findings highlight the association of GER episodes with feeding intolerance and prolonged hospitalization, emphasizing the importance of early GER detection through ETA pepsin measurement. These insights can guide clinical interventions to mitigate complications and improve neonatal outcomes, though further studies are warranted to explore preventive strategies and optimize care in this vulnerable population. |
| Publish Date |
2025-06-16 10:38 |
| Citation |
<p>Elrefaee A, Abdel-Razek ARA, Abdelkhalek ZS, Samaan P, Kamal AF. Incidence of gastro-esophageal reflux disease in mechanically ventilated full-term Egyptian neonates by detection of pepsin in endotracheal aspirate. <i>World J Clin Pediatr</i> 2025; 14(3): 102309</p> |
| URL |
https://www.wjgnet.com/2219-2808/full/v14/i3/102309.htm |
| DOI |
https://dx.doi.org/10.5409/wjcp.v14.i3.102309 |
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