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Articles Published Processes
4/16/2025 5:36:43 AM | Browse: 99 | Download: 384
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Received |
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2024-10-16 01:13 |
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Peer-Review Started |
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2024-10-23 15:44 |
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First Decision by Editorial Office Director |
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2025-02-18 08:40 |
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Return for Revision |
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2025-02-18 08:40 |
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Revised |
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2025-03-04 08:04 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-04-03 02:38 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-04-03 07:17 |
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Articles in Press |
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2025-04-03 07:17 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-04-08 08:11 |
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Publish the Manuscript Online |
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2025-04-16 05:36 |
| ISSN |
2220-315x (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Hematology |
| Manuscript Type |
Minireviews |
| Article Title |
Weak D phenotype in transfusion medicine and obstetrics: Challenges and opportunities
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Prasanna Bharathi Sainath and Velmurugan Ramaiyan |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Velmurugan Ramaiyan, PhD, Professor, Department of Pharmacy, Saveetha College of Pharmacy, Saveetha Institute of Medical and Technical Sciences, NH 48, Chennai 602105, Tamil Nādu, India. ramaiyan.dr@gmail.com |
| Key Words |
Weak D phenotype; Rhesus antigen; RhD blood group genotyping; Allele; Transfusion; Allo-immunization; Pre-natal; Non-invasive prenatal testing; Rhesus immunoglobulin |
| Core Tip |
In this review, we explore the weak D phenotype, caused by Rhesus D antigen (RhD) blood group allele variations, which reduces RhD expression on red blood cells, impacting transfusion strategies and anti-D immunization risks. Molecular and novel genotyping techniques may be necessary for exact identification, and mitigate the risk of alloimmunization in these weak D traits. Implementation challenges such as standardization and financial constraints are quite prevalent in several countries. Hence it emphasizes the importance of accurate weak D phenotype identification and the potential of inculcating molecular techniques in transfusion medicine and obstetrics. |
| Publish Date |
2025-04-16 05:36 |
| Citation |
Sainath PB, Ramaiyan V. Weak D phenotype in transfusion medicine and obstetrics: Challenges and opportunities. World J Exp Med 2025; 15(2): 102345
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| URL |
https://www.wjgnet.com/2220-315x/full/v15/i2/102345.htm |
| DOI |
https://dx.doi.org/10.5493/wjem.v15.i2.102345 |
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