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Articles Published Processes
3/26/2025 10:16:41 AM | Browse: 10 | Download: 43
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Received |
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2024-10-15 16:04 |
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Peer-Review Started |
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2024-10-15 16:04 |
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To Make the First Decision |
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Return for Revision |
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2024-12-26 14:56 |
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Revised |
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2025-01-07 10:48 |
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Second Decision |
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2025-02-13 02:35 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-02-13 08:41 |
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Articles in Press |
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2025-02-13 08:41 |
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Publication Fee Transferred |
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2025-01-15 04:11 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-02-27 05:51 |
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Publish the Manuscript Online |
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2025-03-26 10:16 |
ISSN |
2218-4333 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Minireviews |
Article Title |
Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma
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Manuscript Source |
Unsolicited Manuscript |
All Author List |
Tian-Hao Shen, Xue Yu, Cheng Zhou, Yu Liu, Qiu-Ying Li, Wei Li, Ting-Hui Jiang, Yong-Qiang Zhu and Yan Liu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Yan Liu, MD, Department of Interventional Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164 Lanxi Road, Putuo District, Shanghai, Shanghai 200062, China. 229442695@qq.com |
Key Words |
Cholangiocarcinoma; Biliary-enteric communication of liver-gut axis; Microbiome; Bile acid metabolism; Inflammatory response |
Core Tip |
Cholangiocarcinoma (CCA) is a type of cancer known for its poor prognosis and complex causes. Recently, researchers have focused more on the biliary-enteric axis's role in developing CCA. This review summarizes the basic concepts of the biliary-enteric axis and its potential mechanisms in CCA, including the microbiome's influence, changes in bile acid metabolism, regulation of inflammation, immune system involvement, and interactions in metabolic pathways. We integrate current research findings to explore the multidimensional roles of the biliary-enteric axis in CCA. This approach offers new perspectives for future research and identifies potential therapeutic targets. |
Publish Date |
2025-03-26 10:16 |
Citation |
<p>Shen TH, Yu X, Zhou C, Liu Y, Li QY, Li W, Jiang TH, Zhu YQ, Liu Y. Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma. <i>World J Clin Oncol</i> 2025; 16(4): 102374</p> |
URL |
https://www.wjgnet.com/2218-4333/full/v16/i4/102374.htm |
DOI |
https://dx.doi.org/10.5306/wjco.v16.i4.102374 |
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