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3/26/2025 10:16:41 AM | Browse: 10 | Download: 43
Publication Name World Journal of Clinical Oncology
Manuscript ID 102374
Country China
Received
2024-10-15 16:04
Peer-Review Started
2024-10-15 16:04
To Make the First Decision
Return for Revision
2024-12-26 14:56
Revised
2025-01-07 10:48
Second Decision
2025-02-13 02:35
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-13 08:41
Articles in Press
2025-02-13 08:41
Publication Fee Transferred
2025-01-15 04:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-27 05:51
Publish the Manuscript Online
2025-03-26 10:16
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Minireviews
Article Title Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma
Manuscript Source Unsolicited Manuscript
All Author List Tian-Hao Shen, Xue Yu, Cheng Zhou, Yu Liu, Qiu-Ying Li, Wei Li, Ting-Hui Jiang, Yong-Qiang Zhu and Yan Liu
ORCID
Author(s) ORCID Number
Yan Liu http://orcid.org/0000-0001-7205-1569
Funding Agency and Grant Number
Corresponding Author Yan Liu, MD, Department of Interventional Oncology, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 164 Lanxi Road, Putuo District, Shanghai, Shanghai 200062, China. 229442695@qq.com
Key Words Cholangiocarcinoma; Biliary-enteric communication of liver-gut axis; Microbiome; Bile acid metabolism; Inflammatory response
Core Tip Cholangiocarcinoma (CCA) is a type of cancer known for its poor prognosis and complex causes. Recently, researchers have focused more on the biliary-enteric axis's role in developing CCA. This review summarizes the basic concepts of the biliary-enteric axis and its potential mechanisms in CCA, including the microbiome's influence, changes in bile acid metabolism, regulation of inflammation, immune system involvement, and interactions in metabolic pathways. We integrate current research findings to explore the multidimensional roles of the biliary-enteric axis in CCA. This approach offers new perspectives for future research and identifies potential therapeutic targets.
Publish Date 2025-03-26 10:16
Citation <p>Shen TH, Yu X, Zhou C, Liu Y, Li QY, Li W, Jiang TH, Zhu YQ, Liu Y. Review of the mechanisms of the biliary-enteric axis in the development of cholangiocarcinoma. <i>World J Clin Oncol</i> 2025; 16(4): 102374</p>
URL https://www.wjgnet.com/2218-4333/full/v16/i4/102374.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i4.102374
Full Article (PDF) WJCO-16-102374-with-cover.pdf
Manuscript File 102374_Auto_Edited_013542.docx
Answering Reviewers 102374-answering-reviewers.pdf
Audio Core Tip 102374-audio.m4a
Conflict-of-Interest Disclosure Form 102374-conflict-of-interest-statement.pdf
Copyright License Agreement 102374-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 102374-non-native-speakers.pdf
Peer-review Report 102374-peer-reviews.pdf
Scientific Misconduct Check 102374-scientific-misconduct-check.png
Scientific Editor Work List 102374-scientific-editor-work-list.pdf
CrossCheck Report 102374-crosscheck-report.pdf