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Articles Published Processes
4/18/2025 8:22:09 AM | Browse: 191 | Download: 591
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Received |
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2024-10-15 18:18 |
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Peer-Review Started |
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2024-10-15 18:18 |
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First Decision by Editorial Office Director |
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2025-02-11 09:21 |
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Return for Revision |
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2025-02-11 09:21 |
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Revised |
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2025-02-19 17:07 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-02-26 02:42 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-02-27 08:50 |
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Articles in Press |
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2025-02-27 08:50 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-03-26 02:01 |
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Publish the Manuscript Online |
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2025-04-18 08:22 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Systematic Reviews |
| Article Title |
Islet dimension and its impact on transplant outcome: A systematic review
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Sipra Rout, Pravash R Mishra, Appakalai N Balamurugan and Praveen Kumar Ravi |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Praveen Kumar Ravi, Assistant Professor, MD, Department of Anatomy, All India Institute of Medical Sciences, Sijua, Patrapada, Bhubaneswar 751019, Odisha, India. praveenkumar1059@gmail.com |
| Key Words |
Islet diameter; Transplantation; Islet size; Insulin-secretion; Viability; Engraftment; Insulin independence; Islet transplantation |
| Core Tip |
This systematic review examines the impact of islet size on transplantation outcomes in clinical and preclinical studies. Small islets (< 125 µm) demonstrate superior viability, glucose-stimulated insulin secretion, and engraftment post-transplantation compared to large islets, which suffer from hypoxic injury and poor viability. However, large islets, essential for maintaining euglycemia in vivo, require improved preservation techniques to enhance their post-isolation survival and function. Optimizing islet size and preservation could significantly improve the success of islet transplantation and insulin independence. |
| Publish Date |
2025-04-18 08:22 |
| Citation |
Rout S, Mishra PR, Balamurugan AN, Ravi PK. Islet dimension and its impact on transplant outcome: A systematic review. World J Transplant 2025; 15(3): 102383 |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i3/102383.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i3.102383 |
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