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Articles Published Processes
2/21/2025 10:12:58 AM | Browse: 43 | Download: 70
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Received |
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2024-10-16 21:22 |
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Peer-Review Started |
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2024-10-16 21:22 |
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To Make the First Decision |
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Return for Revision |
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2024-12-02 02:39 |
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Revised |
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2024-12-10 14:49 |
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Second Decision |
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2025-01-09 02:45 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-01-09 09:47 |
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Articles in Press |
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2025-01-09 09:47 |
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Publication Fee Transferred |
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2024-12-18 02:15 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-01-22 10:18 |
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Publish the Manuscript Online |
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2025-02-21 10:12 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Transplantation |
| Manuscript Type |
Retrospective Cohort Study |
| Article Title |
Novel association between graft rejection and post-transplant malignancy in solid organ transplantation
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Hye Sung Kim, Wongi Woo, Young-Geun Choi, Ankit Bharat and Young Kwang Chae |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Young Kwang Chae, MD, Professor, Department of Medicine, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, 645 N. Michigan Avenue, Suite 1006, Chicago, IL 60611, United States. chaelabmeeting@gmail.com |
| Key Words |
Graft rejection; Post-transplant malignancy; Transplantation; Transplant immunology; Immunosuppression; Kidney transplant; Liver transplant; Heart transplant; Lung transplant; Pancreas transplant |
| Core Tip |
Our study uncovers a novel inverse relationship between rejection-induced graft failure (RGF) and post-transplant malignancy (PTM) in a cohort of 579905 solid organ transplant recipients. The findings suggest that immune activation during rejection enhances tumor surveillance and lowers malignancy risk, particularly in kidney transplants. In contrast, the immunosuppressive environment associated with PTM reduces the risk of RGF in all organs except the pancreas. These results underscore the need for tailored immunosuppressive strategies that balance the dual risks of rejection and malignancy to improve long-term outcomes in transplant recipients. |
| Publish Date |
2025-02-21 10:12 |
| Citation |
<p>Kim HS, Woo W, Choi YG, Bharat A, Chae YK. Novel association between graft rejection and post-transplant malignancy in solid organ transplantation. <i>World J Transplant</i> 2025; 15(2): 102384</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i2/102384.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i2.102384 |
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