Publication Name	World Journal of Clinical Oncology
Manuscript ID	102397
Country	China

Received	2024-10-16 07:46
Peer-Review Started	2024-10-16 07:46
To Make the First Decision
Return for Revision	2024-11-26 10:59
Revised	2024-12-04 19:08
Second Decision	2025-02-05 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-06 09:54
Articles in Press	2025-02-06 09:54
Publication Fee Transferred	2024-12-11 13:29
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-05 02:01
Publish the Manuscript Online	2025-03-26 10:16

ISSN	2218-4333 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Oncology
Manuscript Type	Meta-Analysis
Article Title	Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer: A meta-analysis
Manuscript Source	Unsolicited Manuscript
All Author List	Hong-Chang Yang, Cheng-Feng Fu, Li-Jun Qiao, Gen-He Long, Li-Fen Yang and Biao Yao
ORCID	Author(s) ORCID Number Cheng-Feng Fu http://orcid.org/0000-0001-6724-8922
Funding Agency and Grant Number
Corresponding Author	Cheng-Feng Fu, Department of Oncology, Tongren People’s Hospital, No. 120 Taoyuan Avenue, Tongren 554300, Guizhou Province, China. fcf930128@163.com
Key Words	Helicobacter pylori; Gastric cancer; Programmed cell death protein 1/programmed death-ligand 1; Immune checkpoint blockade therapy; Pathogenesis
Core Tip	This meta-analysis investigated the relationship between Helicobacter pylori infection and programmed death-ligand 1 expression in gastric cancer (GC). Fourteen studies with 3069 GC patients were included. Results showed a significant association. Sensitivity and subgroup analyses confirmed the robustness. Publication bias was minimal. Helicobacter pylori infection may influence the response to programmed cell death protein 1/programmed death-ligand 1 blockade therapy in GC patients, but further research is needed to clarify the underlying mechanisms and clinical implications.
Publish Date	2025-03-26 10:16
Citation	<p>Yang HC, Fu CF, Qiao LJ, Long GH, Yang LF, Yao B. Relationship between Helicobacter pylori infection and programmed death-ligand 1 in gastric cancer: A meta-analysis. <i>World J Clin Oncol</i> 2025; 16(4): 102397</p>
URL	https://www.wjgnet.com/2218-4333/full/v16/i4/102397.htm
DOI	https://dx.doi.org/10.5306/wjco.v16.i4.102397

Full Article (PDF)	WJCO-16-102397-with-cover.pdf
PRISMA 2009 Checklist	102397-PRISMA-2009-Checklist.pdf
Manuscript File	102397_Auto_Edited_022051.docx
Answering Reviewers	102397-answering-reviewers.pdf
Audio Core Tip	102397-audio.m4a
Biostatistics Review Certificate	102397-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form	102397-conflict-of-interest-statement.pdf
Copyright License Agreement	102397-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	102397-non-native-speakers.pdf
Peer-review Report	102397-peer-reviews.pdf
Scientific Misconduct Check	102397-scientific-misconduct-check.png
Scientific Editor Work List	102397-scientific-editor-work-list.pdf
CrossCheck Report	102397-crosscheck-report.pdf