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Articles Published Processes
2/24/2025 5:39:16 AM | Browse: 144 | Download: 648
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Received |
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2024-10-16 08:53 |
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Peer-Review Started |
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2024-10-16 08:53 |
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First Decision by Editorial Office Director |
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2024-12-13 08:13 |
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Return for Revision |
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2024-12-13 08:13 |
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Revised |
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2024-12-21 04:37 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2025-01-16 02:35 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-01-16 06:43 |
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Articles in Press |
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2025-01-16 06:43 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-01-24 09:38 |
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Publish the Manuscript Online |
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2025-02-24 05:39 |
| ISSN |
1948-0210 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Biology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Impact of miR-214-5p and miR-21-5p from hypoxic endometrial exosomes on human umbilical cord mesenchymal stem cell function
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| Manuscript Source |
Invited Manuscript |
| All Author List |
Jin-Wei Zhang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82170406, 81970238 |
| Royal Society United Kingdom |
IEC\NSFC\201094 |
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| Corresponding Author |
Jin-Wei Zhang, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, No. 345 Lingling Road, Shanghai 200032, China. jinweizhang@sioc.ac.cn |
| Key Words |
MiR-214-5p; MiR-21-5p; Hypoxic endometrial epithelial cells; Exosomes; Human umbilical cord mesenchymal stem cells; Signal transducer and activator of transcription 3 signaling; Thin endometrium; Infertility |
| Core Tip |
This manuscript examines the study by Zhang et al on the effects of miR-214-5p and miR-21-5p in hypoxic endometrial epithelial-cell-derived exosomes on human umbilical cord mesenchymal stem cells. The study highlights how low expression levels of these microRNAs activate the signal transducer and activator of transcription 3 signaling pathway, promoting human umbilical cord mesenchymal stem cell migration and differentiation - key processes in tissue repair and regeneration. These findings offer new insights into addressing thin endometrium, a common cause of infertility, by leveraging exosome-based therapies or targeted microRNA modulation. This article underscores the potential of miR-214-5p and miR-21-5p as therapeutic targets for improving endometrial health and reproductive outcomes. |
| Publish Date |
2025-02-24 05:39 |
| Citation |
Zhang JW. Impact of miR-214-5p and miR-21-5p from hypoxic endometrial exosomes on human umbilical cord mesenchymal stem cell function. World J Stem Cells 2025; 17(2): 102404
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| URL |
https://www.wjgnet.com/1948-0210/full/v17/i2/102404.htm |
| DOI |
https://dx.doi.org/10.4252/wjsc.v17.i2.102404 |
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