Publication Name	World Journal of Psychiatry
Manuscript ID	102412
Country	China

Received	2024-10-16 12:32
Peer-Review Started	2024-10-16 12:32
To Make the First Decision
Return for Revision	2024-11-28 09:12
Revised	2024-12-09 04:15
Second Decision	2024-12-24 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-25 12:05
Articles in Press	2024-12-25 12:05
Publication Fee Transferred	2024-12-11 01:52
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-06 01:44
Publish the Manuscript Online	2025-01-14 08:49

ISSN	2220-3206 (online)
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Category	Medicine, Research & Experimental
Manuscript Type	Clinical Trials Study
Article Title	Hemispheric asymmetries and network dysfunctions in adolescent depression: A neuroimaging study using resting-state functional magnetic resonance imaging
Manuscript Source	Unsolicited Manuscript
All Author List	Ying Xiong, Ren-Qiang Yu, Xing-Yu Wang, Shun-Si Liang, Jie Ran, Xiao Li and Yi-Zhi Xu
ORCID	Author(s) ORCID Number Ying Xiong http://orcid.org/0000-0003-3702-3399 Ren-Qiang Yu http://orcid.org/0000-0002-3756-450X Yi-Zhi Xu http://orcid.org/0000-0002-0610-2978
Funding Agency and Grant Number	Funding Agency Grant Number Medical Research Project of the Chongqing Municipal Health Commission No. 2024WSJK110
Corresponding Author	Ying Xiong, Assistant Professor, MD, Department of Hematology, Chongqing General Hospital, Chongqing University, No. 118 Xingguang Avenue, Liangjiang New Area, Chongqing 401147, China. xiongying@stu.cqmu.edu.cn
Key Words	Adolescent depression; Brain network connectivity; Neuroimaging biomarkers; Functional magnetic resonance imaging; Default mode network; Salience network; Hemispheric asymmetry
Core Tip	This study explores the neural underpinnings of adolescent depression by investigating disrupted brain network connectivity through resting-state functional magnetic resonance imaging. Key findings highlight significant hemispheric asymmetries, with enhanced activity in the left visual and default mode networks and reduced engagement in the right hemisphere. Additionally, the overactivity of the right dorsal attention network and hypoactivity of the salience network were observed, indicating impairments in emotional and attentional regulation. These distinct neurobiological markers emphasize the importance of early diagnosis and personalized therapeutic interventions for adolescent depression.
Publish Date	2025-01-14 08:49
Citation	<p>Xiong Y, Yu RQ, Wang XY, Liang SS, Ran J, Li X, Xu YZ. Hemispheric asymmetries and network dysfunctions in adolescent depression: A neuroimaging study using resting-state functional magnetic resonance imaging. <i>World J Psychiatry</i> 2025; 15(2): 102412</p>
URL	https://www.wjgnet.com/2220-3206/full/v15/i2/102412.htm
DOI	https://dx.doi.org/10.5498/wjp.v15.i2.102412

Full Article (PDF)	WJP-15-102412-with-cover.pdf
CONSORT 2010 Statement	102412-CONSORT-2010-statement.pdf
Manuscript File	102412_Auto_Edited_010015.docx
Answering Reviewers	102412-answering-reviewers.pdf
Audio Core Tip	102412-audio.mp4
Biostatistics Review Certificate	102412-biostatistics-statement.pdf
Clinical Trial Registration Statement	102412-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form	102412-conflict-of-interest-statement.pdf
Copyright License Agreement	102412-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	102412-foundation-statement.pdf
Signed Informed Consent Form(s) or Document(s)	102412-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document	102412-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate	102412-non-native-speakers.pdf
Peer-review Report	102412-peer-reviews.pdf
Scientific Misconduct Check	102412-scientific-misconduct-check.png
Scientific Editor Work List	102412-scientific-editor-work-list.pdf
CrossCheck Report	102412-crosscheck-report.png
CrossCheck Report	102412-crosscheck-report.pdf