BPG is committed to discovery and dissemination of knowledge
Articles Published Processes
2/14/2025 10:33:16 AM | Browse: 35 | Download: 57
 |
Received |
|
2024-10-17 07:02 |
|
Peer-Review Started |
|
2024-10-17 07:42 |
 |
To Make the First Decision |
|
|
|
Return for Revision |
|
2024-11-28 09:27 |
|
Revised |
|
2024-11-30 13:27 |
|
Second Decision |
|
2024-12-17 02:41 |
|
Accepted by Journal Editor-in-Chief |
|
|
|
Accepted by Executive Editor-in-Chief |
|
2024-12-17 08:05 |
|
Articles in Press |
|
2024-12-17 08:05 |
|
Publication Fee Transferred |
|
|
|
Edit the Manuscript by Language Editor |
|
|
|
Typeset the Manuscript |
|
2025-01-22 04:19 |
|
Publish the Manuscript Online |
|
2025-02-14 10:33 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
|
| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
|
| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Role of 1,25-dihydroxyvitamin D3 in alleviating hepatic steatosis: Targeting M1 macrophage polarization in non-alcoholic fatty liver disease
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Jin-Wei Zhang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| National Natural Science Foundation of China |
82170406 |
| National Natural Science Foundation of China |
81970238 |
|
| Corresponding Author |
Jin-Wei Zhang, State Key Laboratory of Chemical Biology, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, No. 345 Lingling Road, Shanghai 200032, China. jinweizhang@sioc.ac.cn |
| Key Words |
Vitamin D; Non-alcoholic fatty liver disease; M1 macrophage polarization; Vitamin D receptor pathway; Hepatic steatosis |
| Core Tip |
This letter critically analyzes the study by Luo WJ et al., on the effects of 1,25-dihydroxyvitamin D3 [1,25(OH)2D3] in reducing lipid accumulation in hepatocytes by inhibiting M1 macrophage polarization through the vitamin D receptor-peroxisome proliferator-activated receptor gamma pathway in non-alcoholic fatty liver disease (NAFLD). The study highlights how 1,25(OH)₂D₃ improves lipid metabolism and reduces inflammation, offering promising insights for NAFLD treatment. Future research should focus on dose optimization, detailed molecular mechanisms, and translating findings into human clinical trials to validate vitamin D's therapeutic potential in managing NAFLD. |
| Publish Date |
2025-02-14 10:33 |
| Citation |
<p>Zhang JW. Role of 1,25-dihydroxyvitamin D3 in alleviating hepatic steatosis: Targeting M1 macrophage polarization in non-alcoholic fatty liver disease. <i>World J Gastrointest Oncol</i> 2025; 17(3): 102424</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i3/102424.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i3.102424 |
© 2004-2025 Baishideng Publishing Group Inc. All rights reserved. 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
California Corporate Number: 3537345
