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Articles Published Processes
10/24/2014 5:02:00 PM | Browse: 1139 | Download: 1480
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Received |
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2014-03-21 09:15 |
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Peer-Review Started |
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2014-03-21 11:02 |
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To Make the First Decision |
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2014-04-28 14:28 |
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Return for Revision |
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2014-05-06 09:50 |
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Revised |
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2014-06-16 05:05 |
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Second Decision |
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2014-07-29 09:49 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2014-07-29 10:13 |
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Articles in Press |
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2014-07-29 10:13 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2014-10-22 17:06 |
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Publish the Manuscript Online |
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2014-10-24 17:01 |
Category |
Transplantation |
Manuscript Type |
Review |
Article Title |
Methodological aspects of anti-human leukocyte antigen antibody analysis in solid organ transplantation
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Manuscript Source |
Invited Manuscript |
All Author List |
Andrew L Lobashevsky |
Funding Agency and Grant Number |
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Corresponding Author |
Andrew L Lobashevsky, MD, PhD, Associate Professor, Director, Histocompatibility Laboratory, Department of Medicine, School of Medicine, Indiana University, 702 Barnhill Dr., Room #0615, Indianapolis, IN 46202,
United States. alobashe@iuhealth.org
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Key Words |
Human leukocyte antigen; Transplantation; Antibodies; Solid phase analysis; Flow cytometry |
Core Tip |
In solid organ transplantations the graft outcomes critically depend on the degree of human leukocyte antigen (HLA) matching between the donor and recipient. Although the cellular component of the allogeneic immune response to the transplanted tissue plays a key role, the contribution of antibodies should not be underestimated. The detection of anti-HLA class?Ⅰ?and class Ⅱ antibodies is an important component of the initial work-up of a potential transplant candidate. The introduction of new highly sensitive technologies such as solid-phase based technologies has had a tremendous effect on organ allocation and immunomodulation strategies.
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Publish Date |
2014-10-24 17:01 |
Citation |
Lobashevsky AL. Methodological aspects of anti-human leukocyte antigen antibody analysis in solid organ transplantation. World J Transplant 2014; 4(3): 153-167 |
URL |
http://www.wjgnet.com/2220-3230/full/v4/i3/153.htm |
DOI |
http://dx.doi.org/10.5500/wjt.v4.i3.153 |
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