| ISSN |
1007-9327 (print) and 2219-2840 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Medicine, General & Internal |
| Manuscript Type |
Observational Study |
| Article Title |
Helicobacter pylori infection is linked to metabolic dysfunction and associated steatotic liver disease: A large cross-sectional study
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Lin Ye, Kai Yan, Ze Tian, Zhi-Hua Xiao, Ru-Yi Xie, Zheng-Yuan Xie and Li Tao |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Science and Technology Research Program of Jiangxi Provincial Department of Education |
GJJ210225 |
| 2022 Provincial Health and Wellness Committee Science and Technology Program Projects |
20221096 |
| Jiangxi Provincial Natural Science Foundation's Young Scientists Fund |
20242BAB20358 |
|
| Corresponding Author |
Li Tao, Department of Gastroenterology, the Second Affiliated Hospital of Nanchang University, 01 Minde Road, Nanchang City, Jiangxi Province, Postal Code 330008, China, Nanchang 330008, Jiangxi Province, China. ndefy17088@ncu.edu.cn |
| Key Words |
Helicobacter pylori; Obesity; Blood glucose; Lipid profile; Blood pressure; Metabolic dysfunction-associated steatotic liver disease |
| Core Tip |
This large cross-sectional study involving 28624 adults revealed that Helicobacter pylori (H. pylori) infection is correlated with metabolic disturbances, particularly in obese and older individuals. H. pylori-positive individuals exhibited elevated blood glucose, low-density lipoprotein cholesterol, and blood pressure levels, with worse metabolic profiles being observed in patients with metabolic dysfunction-associated steatotic liver disease (MASLD). High blood glucose, body mass index, and diastolic pressure levels were identified as significant risk factors for H. pylori infection, whereas high-density lipoprotein was observed to be a protective factor. These findings suggest that H. pylori infection may contribute to metabolic disorders and MASLD progression, thereby offering insights for future research and prevention strategies. |
| Publish Date |
2025-04-02 10:54 |
| Citation |
<p>Ye L, Yan K, Tian Z, Xiao ZH, Xie RY, Xie ZY, Tao L. Helicobacter pylori infection is linked to metabolic dysfunction and associated steatotic liver disease: A large cross-sectional study. <i>World J Gastroenterol</i> 2025; 31(13): 102563</p> |
| URL |
https://www.wjgnet.com/1007-9327/full/v31/i13/102563.htm |
| DOI |
https://dx.doi.org/10.3748/wjg.v31.i13.102563 |
