Publication Name	World Journal of Gastroenterology
Manuscript ID	102632
Country	China

Received	2024-10-24 03:24
Peer-Review Started	2024-10-24 03:24
To Make the First Decision
Return for Revision	2024-11-16 05:13
Revised	2024-11-21 07:23
Second Decision	2024-12-18 02:37
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2024-12-18 07:03
Articles in Press	2024-12-18 07:03
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-01-09 09:35
Publish the Manuscript Online	2025-01-20 07:38

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis
Manuscript Source	Invited Manuscript
All Author List	Shi Li, Yue Xi, Xue-Ying Dong, Wen-Bin Yuan, Jing-Feng Tang and Ce-Fan Zhou
ORCID	Author(s) ORCID Number Jing-Feng Tang http://orcid.org/0000-0002-5524-4518 Ce-Fan Zhou http://orcid.org/0000-0003-0680-3843
Funding Agency and Grant Number	Funding Agency Grant Number National Natural Science Foundation of China 32270768, 82273970, 32070726, 82370715 National Key R&D Program of China 2023YFC2507904 Innovation Group Project of Hubei Province 2023AFA026
Corresponding Author	Ce-Fan Zhou, School of Life and Health Sciences, Institute of Biomedical Research, National “111” Center for Cellular Regulation and Molecular Pharmaceutics, Key Laboratory of Fermentation Engineering (Ministry of Education), Hubei University of Technology, No. 28 Nanli Road, Wuhan 430068, Hubei Province, China. cefan@hbut.edu.cn
Key Words	Hepatitis B virus; Gene polymorphisms; Multi-clustering analysis; Genetic markers; Personalized medicine; Clinical implications
Core Tip	A significant correlation has been identified between polymorphisms of human leukocyte antigen-DP-DQ and the risk of liver cirrhosis and hepatocellular carcinoma linked to hepatitis B virus infection. In this article, we aim to highlight this study has the potential to transform personalized medical treatments and prevention strategies through the identification of key molecular markers. Additionally, incorporating other upregulated genes related to hepatitis B virus infection could uncover additional genetic markers, greatly enhancing the management and treatment of liver disease.
Publish Date	2025-01-20 07:38
Citation	<p>Li S, Xi Y, Dong XY, Yuan WB, Tang JF, Zhou CF. Evaluating the scope of human leukocyte antigen polymorphisms influencing hepatitis B virus-related liver cancer and cirrhosis through multi-clustering analysis. <i>World J Gastroenterol</i> 2025; 31(7): 102632</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i7/102632.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i7.102632

Full Article (PDF)	WJG-31-102632-with-cover.pdf
Manuscript File	102632_Auto_Edited_082024.docx
Answering Reviewers	102632-answering-reviewers.pdf
Audio Core Tip	102632-audio.m4a
Conflict-of-Interest Disclosure Form	102632-conflict-of-interest-statement.pdf
Copyright License Agreement	102632-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	102632-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	102632-non-native-speakers.pdf
Peer-review Report	102632-peer-reviews.pdf
Scientific Misconduct Check	102632-scientific-misconduct-check.png
Scientific Editor Work List	102632-scientific-editor-work-list.pdf
CrossCheck Report	102632-crosscheck-report.pdf