| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Review |
| Article Title |
Update on the roles and applications of extracellular vesicles in depression
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing Wu, Jian Lu, Ming-Zhi Pan, Xiao-chu Gu, Lu Dai, Yun Wang, Bin Shen and Xiao-Bin Zhang |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Gusu Talent program |
(2023)105 |
| Suzhou Science and Technology Development Plan Program |
SKY2023228 |
| Project of Medical Research Fund of Jiangsu Provincial Health Commission |
Z2023043 |
| Suzhou Clinical Medical Center for Mood Disorders |
Szlcyxzx202109 |
| Suzhou Clinical Key Disciplines for Geriatric Psychiatry |
SZXK202116 |
|
| Corresponding Author |
Jing Wu, PhD, Laboratory Medicine, The Affiliated Guangji Hospital of Soochow University, No. 11 Guangqian Road, Xiangcheng District, Suzhou 215137, Jiangsu Province, China. 1156746344@qq.com |
| Key Words |
Depression; Extracellular vesicles; Exosomes; Biomarkers; Different sources |
| Core Tip |
Depression is a prevalent mental disorder that affects numerous individuals, manifesting as persistent anhedonia, sadness, and hopelessness. Extracellular vesicles (EVs) are phospholipid membrane-enclosed structures that exhibit diversity in size, origin, activity, composition, and function. They encapsulate a myriad of biomolecules, including proteins, lipids, nucleic acids, and metabolites, contributing significantly to intercellular communication across various physiological and pathological progress. We herein summarize an overview of the latest research on EVs from different sources and their roles and potential applications in depression. |
| Publish Date |
2025-02-26 04:37 |
| Citation |
<p>Wu J, Lu J, Pan MZ, Gu XC, Dai L, Wang Y, Shen B, Zhang XB. Update on the roles and applications of extracellular vesicles in depression. <i>World J Psychiatry</i> 2025; 15(3): 102643</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i3/102643.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i3.102643 |
