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Articles Published Processes
2/21/2025 10:13:10 AM | Browse: 38 | Download: 21
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Received |
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2024-10-25 05:49 |
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Peer-Review Started |
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2024-10-25 05:49 |
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To Make the First Decision |
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Return for Revision |
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2024-11-14 08:21 |
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Revised |
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2024-12-09 19:44 |
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Second Decision |
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2025-01-23 02:37 |
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Accepted by Journal Editor-in-Chief |
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Accepted by Executive Editor-in-Chief |
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2025-01-23 09:02 |
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Articles in Press |
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2025-01-23 09:02 |
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Publication Fee Transferred |
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2024-12-12 19:28 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-02-08 07:54 |
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Publish the Manuscript Online |
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2025-02-21 10:13 |
| ISSN |
2220-3230 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Health Care Sciences & Services |
| Manuscript Type |
Observational Study |
| Article Title |
Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Andrew P Beyer, Pamela A Moise, Michael Wong, Wei Gao, Cheryl Xiang, Pangsibo Shen, Martha Pavlakis, Flavio Vincenti and Weijia Wang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Weijia Wang, Value and Implementation Outcomes Research, Merck, 126 E Lincoln Ave, Rahway, NJ 07065, United States. weijia.wang@merck.com |
| Key Words |
Clinical outcome; Healthcare resource use; Kidney transplant; Leukopenia; Neutropenia; Ganciclovir; Valganciclovir |
| Core Tip |
This observational study examined the impact of neutropenia and leukopenia up to 5 years in kidney transplant recipients who received valganciclovir or ganciclovir as cytomegalovirus (CMV) prophylaxis. The results showed that neutropenia and/or leukopenia were associated with increased risks of CMV-related events, opportunistic infections, hospitalizations, and use of granulocyte colony-stimulating factor. Additionally, patients with neutropenia and/or leukopenia had higher healthcare resource utilization, including more inpatient admissions, outpatient visits, and labs. These findings highlight the need for alternative prophylactic treatments for CMV with fewer myelosuppressive effects to improve outcomes in kidney transplant recipients. |
| Publish Date |
2025-02-21 10:13 |
| Citation |
<p>Beyer AP, Moise PA, Wong M, Gao W, Xiang C, Shen P, Pavlakis M, Vincenti F, Wang W. Clinical events and healthcare resource utilization associated with neutropenia and leukopenia among adult kidney transplant recipients receiving valganciclovir. <i>World J Transplant</i> 2025; 15(2): 102671</p> |
| URL |
https://www.wjgnet.com/2220-3230/full/v15/i2/102671.htm |
| DOI |
https://dx.doi.org/10.5500/wjt.v15.i2.102671 |
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