Publication Name	World Journal of Methodology
Manuscript ID	102688
Country	India

Received	2024-10-28 03:45
Peer-Review Started	2024-10-28 03:46
To Make the First Decision
Return for Revision	2024-12-07 23:09
Revised	2024-12-31 07:32
Second Decision	2025-01-10 02:36
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-01-11 09:40
Articles in Press	2025-01-11 09:40
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-14 02:40
Publish the Manuscript Online	2025-03-06 10:23

ISSN	2222-0682 (online)
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Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Sotatercept: A novel therapeutic approach for pulmonary arterial hypertension through transforming growth factor-β signaling modulation
Manuscript Source	Invited Manuscript
All Author List	Jyoti Bajpai, Mehul Saxena, Akshyaya Pradhan and Surya Kant
ORCID	Author(s) ORCID Number Jyoti Bajpai http://orcid.org/0000-0001-6337-856X Akshyaya Pradhan http://orcid.org/0000-0002-2360-7580 Surya Kant http://orcid.org/0000-0001-7520-5404
Funding Agency and Grant Number
Corresponding Author	Jyoti Bajpai, MD, Department of Respiratory Medicine, King George’s Medical University, Shahmina Road, Chowk, Lucknow 226003, Uttar Pradesh, India. jyotibajpai33@gmail.com
Key Words	Protein; Transforming growth factor-β pathway; Mean pulmonary artery pressure; Drugs; Pulmonary artery
Core Tip	Sotatercept is an activin receptor type IIA-Fc fusion protein that improve pulmonary artery pressure as well as cardiopulmonary function in pulmonary artery hypertension. It is administered as a subcutaneous injection every three weeks. There are three different pathways involve in pathogenesis of pulmonary arterial hypertension. Recently, a new pathway for pathogenesis of pulmonary arterial hypertension cellular proliferation has been discovered.
Publish Date	2025-03-06 10:23
Citation	<p>Bajpai J, Saxena M, Pradhan A, Kant S. Sotatercept: A novel therapeutic approach for pulmonary arterial hypertension through transforming growth factor-β signaling modulation. <i>World J Methodol</i> 2025; 15(3): 102688</p>
URL	https://www.wjgnet.com/2222-0682/full/v15/i3/102688.htm
DOI	https://dx.doi.org/10.5662/wjm.v15.i3.102688

Full Article (PDF)	WJM-15-102688-with-cover.pdf
Manuscript File	102688_Auto_Edited_011847.docx
Answering Reviewers	102688-answering-reviewers.pdf
Audio Core Tip	102688-audio.m4a
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Peer-review Report	102688-peer-reviews.pdf
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Scientific Editor Work List	102688-scientific-editor-work-list.pdf
CrossCheck Report	102688-crosscheck-report.pdf