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Articles Published Processes
3/25/2025 4:19:10 PM | Browse: 151 | Download: 649
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Received |
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2024-10-28 03:41 |
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Peer-Review Started |
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2024-10-28 03:41 |
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First Decision by Editorial Office Director |
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2025-01-10 09:35 |
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Return for Revision |
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2025-01-10 09:35 |
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Revised |
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2025-01-23 09:29 |
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Publication Fee Transferred |
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2025-01-26 09:01 |
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Second Decision by Editor |
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2025-02-17 02:46 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2025-02-17 07:13 |
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Articles in Press |
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2025-02-17 07:13 |
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Edit the Manuscript by Language Editor |
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2025-02-18 17:45 |
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Typeset the Manuscript |
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2025-03-02 14:45 |
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Publish the Manuscript Online |
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2025-03-25 16:19 |
| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Case Report |
| Article Title |
Precision treatment for human epidermal growth factor receptor 2-amplified advanced rectal cancer: A case report
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Xia Xiao, Qing-Wen Wang, Zheng-Yang Zhou, Lei-Sheng Wang and Pei Huang |
| ORCID |
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| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Jiangsu Provincial Health and Family Planning Commission Personnel Talent Project |
No. R2017005 |
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| Corresponding Author |
Lei-Sheng Wang, Wuxi Medical College, Jiangnan University, Binhu Road, Wuxi 214122, Jiangsu Province, China. 6222809140@stu.jiangnan.edu.cn |
| Key Words |
Rectal cancer; Human epidermal growth factor receptor 2; Programmed death 1; Pyrotinib; Chemotherapy; Case report |
| Core Tip |
This human epidermal growth factor receptor 2-amplified advanced rectal cancer was unresponsive to conventional chemotherapy and targeted therapy in a Chinese patient. This study demonstrated the synergistic effect of combining an immune checkpoint inhibitor with pyrotinib, providing a new treatment strategy for patients with advanced rectal cancer. Following treatment with an immune checkpoint inhibitor in combination with pyrotinib, the patient achieved significant therapeutic effects as evidenced by a marked reduction in tumour size. |
| Publish Date |
2025-03-25 16:19 |
| Citation |
Xiao X, Wang QW, Zhou ZY, Wang LS, Huang P. Precision treatment for human epidermal growth factor receptor 2-amplified advanced rectal cancer: A case report. World J Gastrointest Oncol 2025; 17(4): 102690 |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i4/102690.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i4.102690 |
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