| Category |
Gastroenterology & Hepatology |
| Manuscript Type |
Clinical Trials Study |
| Article Title |
Covert hepatic encephalopathy: Agreement and predictive validity of different indices
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Sara Montagnese, Esmeralda Balistreri, Sami Schiff, Michele De Rui, Paolo Angeli, Giacomo Zanus, Umberto Cillo, Giancarlo Bombonato, Massimo Bolognesi, David Sacerdoti, Angelo Gatta, Carlo Merkel and Piero Amodio |
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Italian Ministry of Health (Giovani Ricercatori 2009, in Part) |
to Sara Montagnese |
| University of Padova |
to Piero Amodio |
| Foundation Lionello Forin Hepatos Onlus, Padova, Italy |
|
|
| Corresponding Author |
Sara Montagnese, MD, Department of Medicine, University of Padova, Via Giustiniani 2, 35128 Padova, Italy. sara.montagnese@unipd.it |
| Key Words |
Hepatic encephalopathy; Electroencephalography; Psychometry; Ammonia; Liver cirrhosis |
| Core Tip |
Covert hepatic encephalopathy is a heterogeneous entity, which should probably be sought for by a combination of clinical, neurophysiological and neuropsychological indices. Grade Ⅰ hepatic encephalopathy (HE), as diagnosed by an experienced clinician, holds prognostic relevance and is associated with a higher degree of hepatic failure. Thus, while its use as an outcome for clinical trials is not recommended, the abolition of Grade Ⅰ HE seems premature. |
| Publish Date |
2014-11-17 15:12 |
| Citation |
Montagnese S, Balistreri E, Schiff S, De Rui M, Angeli P, Zanus G, Cillo U, Bombonato G, Bolognesi M, Sacerdoti D, Gatta A, Merkel C, Amodio P. Covert hepatic encephalopathy: Agreement and predictive validity of different indices. World J Gastroenterol 2014; 20(42): 15756-15762 |
| URL |
http://www.wjgnet.com/1007-9327/full/v20/i42/15756.htm |
| DOI |
http://dx.doi.org/10.3748/wjg.v20.i42.15756 |
