| ISSN |
2220-3206 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Psychiatry |
| Manuscript Type |
Case Control Study |
| Article Title |
Structural network communication differences in drug-naive depressed adolescents with non-suicidal self-injury and suicide attempts
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Shuai Wang, Jiao-Long Qin, Lian-Lian Yang, Ying-Ying Ji, Hai-Xia Huang, Xiao-Shan Gao, Zi-Mo Zhou, Zhen-Ru Guo, Ye Wu, Lin Tian, Huang-Jing Ni and Zhen-He Zhou |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Chinese National Science Foundation |
No. 81871081 and No. 62201265 |
| Fundamental Research Funds for the Central Universities |
No. NJ2024029-14 |
| Talent Support Programs of Wuxi Health Commission |
No. BJ2023085, FZXK2021012, and M202358 |
|
| Corresponding Author |
Zhen-He Zhou, MD, PhD, Professor, School of Wuxi Medicine, Nanjing Medical University, No. 156 Qianhu Road, Binhu District, Wuxi 214000, Jiangsu Province, China. zhouzh@njmu.edu.cn |
| Key Words |
Depression; Non-suicidal self-injury; Suicide attempts; Adolescents; Communication models; Structural network efficiency |
| Core Tip |
This study investigates structural network communication differences in depressed adolescents, highlighting impaired brain network efficiency in those with non-suicidal self-injury and suicide attempts. Using diffusion magnetic resonance imaging, the research identifies disrupted cortico-cortical and cortico-subcortical circuits, particularly in regions such as the posterior cingulate gyrus and nucleus accumbens. The findings suggest that compromised neural communication is linked to clinical symptoms, offering new insights into the neurobiological mechanisms behind the comorbidity of non-suicidal self-injury and suicide attempts in depression. |
| Publish Date |
2025-04-30 08:58 |
| Citation |
<p>Wang S, Qin JL, Yang LL, Ji YY, Huang HX, Gao XS, Zhou ZM, Guo ZR, Wu Y, Tian L, Ni HJ, Zhou ZH. Structural network communication differences in drug-naive depressed adolescents with non-suicidal self-injury and suicide attempts. <i>World J Psychiatry</i> 2025; 15(5): 102706</p> |
| URL |
https://www.wjgnet.com/2220-3206/full/v15/i5/102706.htm |
| DOI |
https://dx.doi.org/10.5498/wjp.v15.i5.102706 |
