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6/16/2025 10:38:29 AM | Browse: 3 | Download: 24
Publication Name World Journal of Clinical Pediatrics
Manuscript ID 102741
Country United States
Received
2024-10-28 09:49
Peer-Review Started
2024-10-28 09:49
To Make the First Decision
Return for Revision
2025-02-28 05:40
Revised
2025-03-27 23:56
Second Decision
2025-04-10 03:10
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-11 01:47
Articles in Press
2025-04-11 01:47
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-06-06 09:21
Publish the Manuscript Online
2025-06-16 10:38
ISSN 2219-2808 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/
Copyright ©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Surgery
Manuscript Type Case Report
Article Title Diagnostic and management challenges in a partially infarcted borderline phyllodes tumor in an adolescent female: A case report and review of literature
Manuscript Source Unsolicited Manuscript
All Author List Elizabeth Suschana, Flora Mae Sta Ines, Padmini Manrai, Susan Koelliker, Jennifer S Gass and Yun-An Tseng
ORCID
Author(s) ORCID Number
Elizabeth Suschana http://orcid.org/0009-0003-0648-0295
Yun-An Tseng http://orcid.org/0009-0009-1785-4727
Funding Agency and Grant Number
Corresponding Author Yun-An Tseng, Pathology and Laboratory Medicine, Women and Infants Hospital, Warren Alpert Medical School of Brown University, 101 Dudley St, Providence, RI 02905, United States. yatseng@kentri.org
Key Words Borderline phyllodes tumor; Adolescent breast tumor; Infarction; Diagnostic challenge; Local recurrence; Surgical margins; Case report
Core Tip The primary goal of evaluation in pediatric breast masses is to do no harm. However, rapidly growing and symptomatic masses require a more extensive work-up, including biopsy and surgical excision. We present a rapidly growing breast mass in a 14-year-old female, which was diagnosed as a borderline phyllodes tumor (PT) on her excision specimen. The mass rapidly enlarged over 24 hours. The initial biopsy pathology was limited due to a large area of infarction. The patient underwent excision of the mass. Final pathology confirmed a borderline PT that extended into the surgical margin, resulting in an additional re-excision procedure. Accurate diagnosis prior to surgical intervention is crucial to avoid additional procedures. Although histological morphology remains the gold standard for diagnosis, immunohistochemistry and molecular studies have recently shown to improve the accuracy of diagnosis of PTs. Long-term clinical and pathologic follow-up of PTs in adolescent patients should be collectively studied to examine whether our current diagnostic criteria for PT can reliably predict tumor behavior in this age group.
Publish Date 2025-06-16 10:38
Citation <p>Suschana E, Sta Ines FM, Manrai P, Koelliker S, Gass JS, Tseng YA. Diagnostic and management challenges in a partially infarcted borderline phyllodes tumor in an adolescent female: A case report and review of literature. <i>World J Clin Pediatr</i> 2025; 14(3): 102741</p>
URL https://www.wjgnet.com/2219-2808/full/v14/i3/102741.htm
DOI https://dx.doi.org/10.5409/wjcp.v14.i3.102741
Full Article (PDF) WJCP-14-102741-with-cover.pdf
CARE Checklist–2016 102741-CARE-Checklist-2016.pdf
Manuscript File 102741_Auto_Edited_042538.docx
Answering Reviewers 102741-answering-reviewers.pdf
Audio Core Tip 102741-audio.m4a
Conflict-of-Interest Disclosure Form 102741-conflict-of-interest-statement.pdf
Copyright License Agreement 102741-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 102741-informed-consent-statement.pdf
Peer-review Report 102741-peer-reviews.pdf
Scientific Misconduct Check 102741-scientific-misconduct-check.png
Scientific Editor Work List 102741-scientific-editor-work-list.pdf
CrossCheck Report 102741-crosscheck-report.pdf