Category |
Imaging Science & Photographic Technology |
Manuscript Type |
Prospective Study |
Article Title |
Attenuation imaging: Diagnostic differences in hepatic steatosis for chronic hepatitis B vs metabolic dysfunction-associated steatotic liver disease patients
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
Xue-Qi Li, Guang-Wen Cheng, Iwaki Akiyama, Xian-Jue Huang, Jing Liang, Li-Yun Xue, Yi Cheng, Masatoshi Kudo and Hong Ding |
ORCID |
|
Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
No. 82202185 |
Shanghai Science and Technology Development Foundation |
No. 22Y11911500 |
|
Corresponding Author |
Hong Ding, PhD, Professor, Department of Ultrasound, National Clinical Research Center for Aging and Medicine, Huashan Hospital, Fudan University, No. 12 Urumqi Middle Road, Shanghai 200040, China. ding_hong@fudan.edu.cn |
Key Words |
Metabolic dysfunction-associated steatotic liver disease; Chronic hepatitis B; Liver steatosis; Attenuation imaging; Attenuation coefficient |
Core Tip |
Our study demonstrated that for the same steatosis grade, the attenuation coefficient (AC) value was significantly higher in the metabolic dysfunction-associated steatotic liver disease (MASLD) group than that in the chronic hepatitis B group. AC effectively discriminated between the degree of steatosis in steatotic liver disease of various etiologies. In the MASLD group, to improve the ability to predict ≥ S2, a clinical model incorporating blood biochemical parameters and AC was established, with an area under the curve of 0.848. The predictive model demonstrated a sensitivity of 91.2% and a specificity of 71.8%. |
Publish Date |
2025-03-13 10:11 |
Citation |
<p>Li XQ, Cheng GW, Akiyama I, Huang XJ, Liang J, Xue LY, Cheng Y, Kudo M, Ding H. Attenuation imaging: Diagnostic differences in hepatic steatosis for chronic hepatitis B vs metabolic dysfunction-associated steatotic liver disease patients. <i>World J Gastroenterol</i> 2025; 31(11): 102795</p> |
URL |
https://www.wjgnet.com/1007-9327/full/v31/i11/102795.htm |
DOI |
https://dx.doi.org/10.3748/wjg.v31.i11.102795 |