Publication Name	World Journal of Gastrointestinal Oncology
Manuscript ID	102831
Country	China

Received	2024-11-06 11:35
Peer-Review Started	2024-11-06 11:35
To Make the First Decision
Return for Revision	2025-01-03 08:43
Revised	2025-01-17 03:43
Second Decision	2025-02-05 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-05 06:37
Articles in Press	2025-02-05 06:37
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-03-05 02:38
Publish the Manuscript Online	2025-03-25 16:18

ISSN	1948-5204 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Potential biomarkers for the prognosis of gastrointestinal stromal tumors
Manuscript Source	Invited Manuscript
All Author List	Yue-Fang Sun, Xuan-Ke Cao, Qing Wei and Yao-Hui Gao
ORCID	Author(s) ORCID Number Yao-Hui Gao http://orcid.org/0000-0002-6830-5295
Funding Agency and Grant Number
Corresponding Author	Yao-Hui Gao, PhD, Professor, Department of Pathology, Shanghai Tenth People’s Hospital, Tongji University School of Medicine, No. 301 Yanchang Middle Road, Shanghai 200000, China. gaoyaohui187@tongji.edu.cn
Key Words	Gastrointestinal stromal tumors; Prognostic parameters; Inflammatory markers; Recurrence risk; Personalized therapy
Core Tip	The importance of predicting prognosis in the management of gastrointestinal stromal tumors (GIST) is well known, with a particular focus on mitotic activity, tumor size, anatomical location, and KIT and platelet-derived growth factor receptor alpha mutation status. It underscores the emerging significance of inflammatory markers such as the neutrophil-to-lymphocyte ratio, systemic immune-to-inflammation index, platelet-to-lymphocyte ratio (PLR), and monocyte-to-lymphocyte ratio (MLR) in predicting GIST prognosis and recurrence risk. This study identified the MLR and PLR as independent risk factors, thereby providing a predictive model for recurrence-free survival. However, it is important to note that the study has limitations, including its retrospective design, small sample size, and lack of external validation.
Publish Date	2025-03-25 16:18
Citation	<p>Sun YF, Cao XK, Wei Q, Gao YH. Potential biomarkers for the prognosis of gastrointestinal stromal tumors. <i>World J Gastrointest Oncol</i> 2025; 17(4): 102831</p>
URL	https://www.wjgnet.com/1948-5204/full/v17/i4/102831.htm
DOI	https://dx.doi.org/10.4251/wjgo.v17.i4.102831

Full Article (PDF)	WJGO-17-102831-with-cover.pdf
Manuscript File	102831_Auto_Edited_071639.docx
Answering Reviewers	102831-answering-reviewers.pdf
Audio Core Tip	102831-audio.m4a
Conflict-of-Interest Disclosure Form	102831-conflict-of-interest-statement.pdf
Copyright License Agreement	102831-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	102831-non-native-speakers.pdf
Peer-review Report	102831-peer-reviews.pdf
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Scientific Editor Work List	102831-scientific-editor-work-list.pdf
CrossCheck Report	102831-crosscheck-report.pdf