Publication Name	World Journal of Critical Care Medicine
Manuscript ID	102834
Country	United States

Received	2024-10-31 03:35
Peer-Review Started	2024-10-31 03:35
To Make the First Decision
Return for Revision	2025-02-28 06:00
Revised	2025-03-06 05:02
Second Decision	2025-03-14 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-03-14 08:35
Articles in Press	2025-03-14 08:35
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-03-20 11:09
Typeset the Manuscript	2025-07-02 06:50
Publish the Manuscript Online	2025-07-18 15:29

ISSN	2220-3141(online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
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Category	Critical Care Medicine
Manuscript Type	Minireviews
Article Title	Early enteral nutrition in critically-ill patients
Manuscript Source	Invited Manuscript
All Author List	Vishnu Yanamaladoddi, Hannah D’Cunha, Ericka Charley, Vikash Kumar, Aalam Sohal and Wael Youssef
ORCID	Author(s) ORCID Number Vishnu Yanamaladoddi http://orcid.org/0000-0002-0731-2280 Aalam Sohal http://orcid.org/0000-0001-8365-7240
Funding Agency and Grant Number
Corresponding Author	Aalam Sohal, MD, Department of Gastroenterology and Hepatology, Creighton University School of Medicine, 3216 NE 45th Pl Suite 212, Phoenix, AZ 85012, United States. aalamsohal@gmail.com
Key Words	Enteral nutrition; Intensive care unit; Adult; Nutrition; Early enteral nutrition; Critically-ill; Parenteral nutrition
Core Tip	Early enteral nutrition (EEN), initiated within 48 hours of intensive care unit admission, demonstrates significant benefits across various critical care settings. This review highlights EEN’s role in reducing mortality, infections, and intensive care unit length of stay among patients with severe burns, sepsis, gastrointestinal bleeds, acute pancreatitis along with patients in critical cardiac, respiratory and neurological disease states. EEN also modulates immune responses, supports gut integrity, and decreases stress-related complications. Although some recent studies question EEN’s efficacy, the overall evidence supports its adoption as a standard care practice for critically ill patients to enhance recovery without substantial adverse effects.
Publish Date	2025-07-18 15:29
Citation	<p>Yanamaladoddi V, D’Cunha H, Charley E, Kumar V, Sohal A, Youssef W. Early enteral nutrition in critically-ill patients. <i>World J Crit Care Med</i> 2025; 14(3): 102834</p>
URL	https://www.wjgnet.com/2220-3141/full/v14/i3/102834.htm
DOI	https://dx.doi.org/10.5492/wjccm.v14.i3.102834

Full Article (PDF)	WJCCM-14-102834-with-cover.pdf
Manuscript File	102834_Auto_Edited_084711.docx
Answering Reviewers	102834-answering-reviewers.pdf
Audio Core Tip	102834-audio.mp3
Conflict-of-Interest Disclosure Form	102834-conflict-of-interest-statement.pdf
Copyright License Agreement	102834-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	102834-non-native-speakers.pdf
Peer-review Report	102834-peer-reviews.pdf
Scientific Misconduct Check	102834-scientific-misconduct-check.png
Scientific Editor Work List	102834-scientific-editor-work-list.pdf
CrossCheck Report	102834-crosscheck-report.pdf