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5/30/2025 10:57:25 AM | Browse: 7 | Download: 48
Publication Name World Journal of Gastrointestinal Surgery
Manuscript ID 102907
Country China
Received
2025-02-18 08:41
Peer-Review Started
2025-02-18 08:42
To Make the First Decision
Return for Revision
2025-03-14 06:51
Revised
2025-03-24 12:49
Second Decision
2025-04-24 02:41
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-04-24 08:40
Articles in Press
2025-04-24 08:40
Publication Fee Transferred
2025-03-31 04:03
Edit the Manuscript by Language Editor
2025-05-01 04:00
Typeset the Manuscript
2025-05-24 04:29
Publish the Manuscript Online
2025-05-30 10:57
ISSN 1948-9366 (online)
Open Access Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Randomized Controlled Trial
Article Title Effect of dexmedetomidine-ropivacaine transversus abdominis plane block on analgesia and cognitive impairment risk in colorectal cancer surgery
Manuscript Source Unsolicited Manuscript
All Author List Xing Zhang, Guang-Rong Xiang, Zhi-Xin Wang, Ming-Qing Peng and Min Li
ORCID
Author(s) ORCID Number
Xing Zhang http://orcid.org/0009-0004-8635-9651
Ming-Qing Peng http://orcid.org/0009-0000-8675-9197
Funding Agency and Grant Number
Corresponding Author Ming-Qing Peng, Chief Physician, MD, Department of Anesthesiology, Yongchuan Hospital of Chongqing Medical University, No. 439 Xuanhua Road, Yongchuan District, Chongqing 402160, China. 400159@hospital.cqmu.edu.cn
Key Words Radical resection; Colorectal cancer; Dexmedetomidine; Ropivacaine; Transversus abdominis; Plane block
Core Tip The dexmedetomidine plus ropivacaine combination for transversus abdominis plane block significantly improves postoperative outcomes in patients undergoing radical resection for colorectal cancer. This treatment enhances pain control, reduces postoperative cognitive dysfunction, and lowers the levels of serum inflammatory markers and stress hormones, such as cortisol and adrenaline. The approach provides a promising strategy for better managing postoperative analgesia and minimizing cognitive decline, particularly in elderly patients. Moreover, it demonstrates a favorable safety profile with fewer adverse reactions compared to traditional analgesic methods, making it a valuable addition to colorectal surgery protocols.
Publish Date 2025-05-30 10:57
Citation <p>Zhang X, Xiang GR, Wang ZX, Peng MQ, Li M. Effect of dexmedetomidine-ropivacaine transversus abdominis plane block on analgesia and cognitive impairment risk in colorectal cancer surgery. <i>World J Gastrointest Surg</i> 2025; 17(6): 102907</p>
URL https://www.wjgnet.com/1948-9366/full/v17/i6/102907.htm
DOI https://dx.doi.org/10.4240/wjgs.v17.i6.102907
Full Article (PDF) WJGS-17-102907-with-cover.pdf
CONSORT 2010 Statement 102907-CONSORT-2010-statement.pdf
Manuscript File 102907_Auto_Edited_064729.docx
Answering Reviewers 102907-answering-reviewers.pdf
Audio Core Tip 102907-audio.mp3
Biostatistics Review Certificate 102907-biostatistics-statement.pdf
Clinical Trial Registration Statement 102907-clinical-trial-registration-statement.pdf
Conflict-of-Interest Disclosure Form 102907-conflict-of-interest-statement.pdf
Copyright License Agreement 102907-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 102907-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 102907-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 102907-non-native-speakers.pdf
Peer-review Report 102907-peer-reviews.pdf
Scientific Misconduct Check 102907-scientific-misconduct-check.png
Scientific Editor Work List 102907-scientific-editor-work-list.pdf
CrossCheck Report 102907-crosscheck-report.pdf