Publication Name	World Journal of Cardiology
Manuscript ID	10291
Country	United States

Received	2014-03-25 08:24
Peer-Review Started	2014-03-25 22:29
To Make the First Decision	2014-04-28 14:34
Return for Revision	2014-04-30 15:14
Revised	2014-05-20 05:21
Second Decision	2014-06-18 15:02
Accepted by Journal Editor-in-Chief
Accepted by Company Editor-in-Chief	2014-06-18 15:20
Articles in Press	2014-06-18 15:45
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2014-08-28 14:01
Publish the Manuscript Online	2014-09-17 14:32

ISSN	1949-8462 (online)
Open Access
Copyright
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Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Cardiac & Cardiovascular Systems
Manuscript Type	Minireviews
Article Title	Long term negative pressure ventilation: Rescue for the failing fontan?
Manuscript Source	Invited Manuscript
All Author List	Shriprasad R Deshpande and Kevin O Maher
Funding Agency and Grant Number
Corresponding Author	Shriprasad R Deshpande, MD, MS, Division of Pediatric Cardiology, Emory University, Children’s Healthcare of Atlanta, 1405 Clifton Rd NE, Atlanta, GA 30322, United States. deshpandes@kidsheart.com
Key Words	Fontan; Single ventricle physiology; Negative pressure ventilation; Cardiorespiratory interactions; Congenital heart disease
Core Tip	In the current surgical era for congenital heart disease, palliation of single ventricle patients has become standard of care. However, pathophysiologic failure after the thrid stage of palliation (Fontan) is commonplace, with very few therapeutic options. Failing Fontan physiology is a management challenge. Herein, we review the pathophysiology of failing Fontan, current therapies and propose a novel way of treating the failing Fontan by utilizing negative pressure ventilation to reverse some of the maladapative changes. This is a hypothesis paper. We think, the ideas central to the manuscript are worth bringing out for intellectual discussion and wider testing.
Publish Date	2014-09-17 14:32
Citation	Deshpande SR, Maher KO. Long term negative pressure ventilation: Rescue for the failing fontan? World J Cardiol 2014; 6(8): 861-864
URL	http://www.wjgnet.com/1949-8462/full/v6/i8/861.htm
DOI	http://dx.doi.org/10.4330/wjc.v6.i8.861

Full Article (PDF)	WJC-6-861.pdf
Full Article (Word)	WJC-6-861.doc
Manuscript File	10291-Review.doc
Answering Reviewers	10291-Answering reviewers.pdf
Copyright License Agreement	10291-Copyright assignment.pdf
Peer-review Report	10291-Peer review(s).pdf
Scientific Misconduct Check	10291-CrossCheck.jpg
Scientific Editor Work List	10291-Scientific editor work list.pdf