Publication Name	World Journal of Psychiatry
Manuscript ID	102953
Country	South Korea

Received	2024-11-04 08:54
Peer-Review Started	2024-11-04 08:54
To Make the First Decision
Return for Revision	2025-02-10 08:24
Revised	2025-02-13 12:17
Second Decision	2025-02-24 02:42
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-24 08:26
Articles in Press	2025-02-24 08:26
Publication Fee Transferred
Edit the Manuscript by Language Editor	2025-02-26 11:52
Typeset the Manuscript	2025-03-14 07:02
Publish the Manuscript Online	2025-04-30 08:58

ISSN	2220-3206 (online)
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Category	Psychiatry
Manuscript Type	Letter to the Editor
Article Title	Unveiling the invisible: How cutting-edge neuroimaging transforms adolescent depression diagnosis
Manuscript Source	Invited Manuscript
All Author List	Haewon Byeon
ORCID	Author(s) ORCID Number Haewon Byeon http://orcid.org/0000-0002-3363-390X
Funding Agency and Grant Number	Funding Agency Grant Number Basic Science Research Program through the National Research Foundation of Korea Funded by the Ministry of Education NRF- RS-2023-00237287
Corresponding Author	Haewon Byeon, Associate Professor, PhD, Worker's Care and Digital Health Lab, Department of Future Technology, Korea University of Technology and Education, 1600 Chungjeol-Ro, Cheonan 31253, South Korea. bhwpuma@naver.com
Key Words	Chronic multimorbidity; High complexity unit; Multidisciplinary approach; Patient-centered care; Integrated care model; Hospitalization metrics
Core Tip	Yu et al's research sheds light on adolescent major depressive disorder (MDD), focusing on the amygdala. The study explores neuroimaging biomarkers for diagnostics using resting-state functional magnetic resonance imaging to analyze functional connectivity (FC) in adolescents with MDD. It found reduced FC in the left inferior temporal gyrus and right lingual gyrus, alongside increased connectivity in Vermis-10. Support vector machines effectively distinguished MDD patients from healthy controls, highlighting reduced FC in the right lingual gyrus as a key marker. These findings suggest FC changes as reliable biomarkers, offering a non-invasive, accurate diagnostic approach for adolescent MDD.
Publish Date	2025-04-30 08:58
Citation	<p>Byeon H. Unveiling the invisible: How cutting-edge neuroimaging transforms adolescent depression diagnosis. <i>World J Psychiatry</i> 2025; 15(5): 102953</p>
URL	https://www.wjgnet.com/2220-3206/full/v15/i5/102953.htm
DOI	https://dx.doi.org/10.5498/wjp.v15.i5.102953

Full Article (PDF)	WJP-15-102953-with-cover.pdf
Manuscript File	102953_Auto_Edited_121001.docx
Answering Reviewers	102953-answering-reviewers.pdf
Audio Core Tip	102953-audio.mp3
Conflict-of-Interest Disclosure Form	102953-conflict-of-interest-statement.pdf
Copyright License Agreement	102953-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	102953-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	102953-non-native-speakers.pdf
Peer-review Report	102953-peer-reviews.pdf
Scientific Misconduct Check	102953-scientific-misconduct-check.png
Scientific Editor Work List	102953-scientific-editor-work-list.pdf
CrossCheck Report	102953-crosscheck-report.pdf