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3/26/2025 10:16:43 AM | Browse: 52 | Download: 395
Publication Name World Journal of Clinical Oncology
Manuscript ID 102958
Country China
Received
2024-11-07 11:01
Peer-Review Started
2024-11-07 11:01
First Decision by Editorial Office Director
2024-12-24 08:07
Return for Revision
2024-12-24 08:45
Revised
2025-01-18 23:09
Publication Fee Transferred
2025-01-24 04:44
Second Decision by Editor
2025-02-24 02:43
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-02-24 09:12
Articles in Press
2025-02-24 09:12
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-03-15 03:18
Publish the Manuscript Online
2025-03-26 10:16
ISSN 2218-4333 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Oncology
Manuscript Type Basic Study
Article Title Downregulation of huntingtin-associated protein 1 predicts poor prognosis in gastric cancer
Manuscript Source Unsolicited Manuscript
All Author List Xiang-Yang Wang, Fu-Hai Yang, Zhong-Yuan Yuan, Zhong-Jing Wang, Hong-Feng Zhang and Zi-Hui Xu
ORCID
Author(s) ORCID Number
Xiang-Yang Wang http://orcid.org/0000-0002-5155-8341
Zhong-Jing Wang http://orcid.org/0000-0002-8684-1200
Zi-Hui Xu http://orcid.org/0000-0001-7081-3195
Funding Agency and Grant Number
Funding Agency Grant Number
Hubei Province Natural Science Foundation Project No. 2021CFB448
Wuhan Municipal Health Commission No. WX23A55
Corresponding Author Zi-Hui Xu, Associate Chief Physician, MD, PhD, Department of Endocrinology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, No. 26 Shengli Street, Wuhan 430014, Hubei Province, China. tj017@163.com
Key Words Huntingtin-associated protein 1; Gastric cancer; Prognostic utility; Biomarker; Clinical stage
Core Tip The clinical utility of huntingtin-associated protein 1 (HAP1) expression in gastric cancer (GC) was assessed. HAP1 expression was significantly lower in GC tissues than in normal gastric mucosa, and was strongly associated with GC progression and metastasis. Downregulation of HAP1 correlates with poor overall survival in patients with GC, especially in advanced clinical stages. Thus, HAP1 is a promising prognostic marker for GC, with important implications for advancing treatment.
Publish Date 2025-03-26 10:16
Citation

Wang XY, Yang FH, Yuan ZY, Wang ZJ, Zhang HF, Xu ZH. Downregulation of huntingtin-associated protein 1 predicts poor prognosis in gastric cancer. World J Clin Oncol 2025; 16(4): 102958

URL https://www.wjgnet.com/2218-4333/full/v16/i4/102958.htm
DOI https://dx.doi.org/10.5306/wjco.v16.i4.102958
Full Article (PDF) WJCO-16-102958-with-cover.pdf
Manuscript File 102958_Auto_Edited_092834.docx
Answering Reviewers 102958-answering-reviewers.pdf
Audio Core Tip 102958-audio.m4a
Biostatistics Review Certificate 102958-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 102958-conflict-of-interest-statement.pdf
Copyright License Agreement 102958-copyright-assignment.pdf
Institutional Review Board Approval Form or Document 102958-institutional-review-board-statement.pdf
Non-Native Speakers of English Editing Certificate 102958-non-native-speakers.pdf
Peer-review Report 102958-peer-reviews.pdf
Scientific Misconduct Check 102958-scientific-misconduct-check.png
Scientific Editor Work List 102958-scientific-editor-work-list.pdf
CrossCheck Report 102958-crosscheck-report.pdf