| ISSN |
1948-5204 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Oncology |
| Manuscript Type |
Retrospective Study |
| Article Title |
Prognostic value of preoperative fibrinogen, neutrophil-to-lymphocyte ratio, serum alpha-fetoprotein, and prealbumin for primary liver cancer undergoing trans-arterial chemoembolization
|
| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Qi-Qi Liu, Ya-Dong Li, Jia-Xin Chen, Lin-Lin Zhang, Rong-Chun Guan, Wei Zhao and Ling-Yu Meng |
| ORCID |
|
| Funding Agency and Grant Number |
| Funding Agency |
Grant Number |
| Health Commission of Heilongjiang Province |
0230404080031 |
|
| Corresponding Author |
Ling-Yu Meng, Clinical Laboratory, The Third Affiliated Hospital of Qiqihar Medical University, No. 3 Taishun Street, Tiefeng District, Qiqihar 161000, Heilongjiang Province, China. 18345202361@163.com |
| Key Words |
Primary liver cancer; Trans-arterial arterial chemoembolization; Prognose; Fibrinogen and neutrophil-to-lymphocyte ratio score; Serum alpha-fetoprotein; Prealbumin |
| Core Tip |
This study investigates the prognostic value of combining fibrinogen and neutrophil-to-lymphocyte ratio (F-NLR) score, alpha-fetoprotein (AFP), and prealbumin (PA) in patients with primary liver cancer undergoing transarterial chemoembolization. Our findings indicate that integrating F-NLR, which reflects systemic inflammation and coagulation status, AFP as a marker of tumor burden, and PA as an indicator of nutritional status and liver function, significantly enhances prognostic accuracy. This combined approach provides a basis for personalized treatment strategies, enabling precise identification of high-risk patients and optimizing therapeutic plans to improve outcomes. |
| Publish Date |
2025-06-13 13:39 |
| Citation |
<p>Liu QQ, Li YD, Chen JX, Zhang LL, Guan RC, Zhao W, Meng LY. Prognostic value of preoperative fibrinogen, neutrophil-to-lymphocyte ratio, serum alpha-fetoprotein, and prealbumin for primary liver cancer undergoing trans-arterial chemoembolization. <i>World J Gastrointest Oncol</i> 2025; 17(6): 103198</p> |
| URL |
https://www.wjgnet.com/1948-5204/full/v17/i6/103198.htm |
| DOI |
https://dx.doi.org/10.4251/wjgo.v17.i6.103198 |
