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Articles Published Processes
1/21/2025 9:22:09 AM | Browse: 218 | Download: 612
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Received |
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2024-11-13 10:24 |
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Peer-Review Started |
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2024-11-13 10:24 |
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First Decision by Editorial Office Director |
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2024-12-13 08:24 |
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Return for Revision |
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2024-12-13 08:24 |
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Revised |
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2024-12-14 16:52 |
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Publication Fee Transferred |
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Second Decision by Editor |
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2024-12-20 03:03 |
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Second Decision by Editor-in-Chief |
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Final Decision by Editorial Office Director |
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2024-12-20 10:32 |
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Articles in Press |
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2024-12-20 10:32 |
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Edit the Manuscript by Language Editor |
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Typeset the Manuscript |
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2025-01-13 01:50 |
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Publish the Manuscript Online |
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2025-01-21 09:22 |
| ISSN |
2218-4333 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
© The Author(s) 2024. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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| Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Respiratory System |
| Manuscript Type |
Letter to the Editor |
| Article Title |
Tankyrase 2 as a therapeutic target in non-small cell lung cancer: Implications for apoptosis and migration
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| Manuscript Source |
Unsolicited Manuscript |
| All Author List |
Jing Yu, Bo-Tao Xu, Qiu Li and Zhong-Tu Shang |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Bo-Tao Xu, Assistant Professor, MD, Postdoctoral Fellow, Department of Cardiothoracic Surgery, Zhuji People’s Hospital, No. 9 Jianmin Road, Taozhu Street, Zhuji 311800, Zhejiang Province, China. 18888755957@163.com |
| Key Words |
Apoptosis; Cell migration; Metastasis; Non-small cell lung cancer; Therapeutic target |
| Core Tip |
Tankyrase 2 (TNKS2) drives the progression of non-small cell lung cancer (NSCLC) by inhibiting apoptosis and promoting cell migration, significantly activating the β-catenin pathway. This function underscores TNKS2's potential as a therapeutic target in NSCLC; however, additional in vivo studies are needed to confirm its role and to evaluate its expression in clinical samples for prognostic use. Combining TNKS2 inhibitors with apoptosis-inducing drugs may enhance therapeutic efficacy, while targeted delivery methods could reduce off-target effects in healthy tissues, advancing the development of TNKS2-focused treatment strategies in NSCLC management. |
| Publish Date |
2025-01-21 09:22 |
| Citation |
Yu J, Xu BT, Li Q, Shang ZT. Tankyrase 2 as a therapeutic target in non-small cell lung cancer: Implications for apoptosis and migration. World J Clin Oncol 2025; 16(3): 103234 |
| URL |
https://www.wjgnet.com/2218-4333/full/v16/i3/103234.htm |
| DOI |
https://dx.doi.org/10.5306/wjco.v16.i3.103234 |
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