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1/21/2025 7:29:06 AM | Browse: 23 | Download: 69
Publication Name World Journal of Clinical Cases
Manuscript ID 103239
Country China
Received
2024-11-13 09:39
Peer-Review Started
2024-11-13 09:39
To Make the First Decision
Return for Revision
2024-12-12 08:11
Revised
2024-12-19 08:47
Second Decision
2025-01-09 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-01-09 10:02
Articles in Press
2025-01-09 10:02
Publication Fee Transferred
2024-12-24 05:07
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-01-15 08:13
Publish the Manuscript Online
2025-01-21 07:29
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Urology & Nephrology
Manuscript Type Case Report
Article Title Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab: A case report
Manuscript Source Unsolicited Manuscript
All Author List Jian-Hui Zhao, Jing-Jiao Wang and Yi-Wen Li
ORCID
Author(s) ORCID Number
Jian-Hui Zhao http://orcid.org/0000-0002-6238-6776
Funding Agency and Grant Number
Corresponding Author Jian-Hui Zhao, Associate Chief Physician, MD, Department of Nephrology, Xinchang County People's Hospital, No. 117 Gushan Middle Road, Nanming Street, Xinchang 312500, Zhejiang Province, China. lyzhaojh@126.com
Key Words Tislelizumab; Programmed cell death-1 inhibitor; Granulomatosis with polyangiitis; Anti-neutrophil cytoplasmic antibody-associated vasculitis; Case report
Core Tip Anti-neutrophil cytoplasmic antibody-associated vasculitis (AAV) due to immune checkpoint inhibitors is extremely rare. AAV caused by the programmed cell death-1 inhibitor, tislelizumab, has not been reported. Our patient developed AAV and granulomatosis with polyangiitis after tislelizumab treatment. Glucocorticoids given in combination with cyclophosphamide effectively treated our patient. However, after the patient discontinued treatment without authorization, the vasculitis recurred. The glucocorticoid + cyclophosphamide regimen was continued, but the patient’s renal function deteriorated.
Publish Date 2025-01-21 07:29
Citation <p>Zhao JH, Wang JJ, Li YW. Granulomatosis with polyangiitis induced by the anti-programmed cell death-1 inhibitor tislelizumab: A case report. <i>World J Clin Cases</i> 2025; 13(15): 103239</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i15/103239.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i15.103239
Full Article (PDF) WJCC-13-103239-with-cover.pdf
CARE Checklist–2016 103239-CARE-Checklist-2016.pdf
Manuscript File 103239_Auto_Edited_061316.docx
Answering Reviewers 103239-answering-reviewers.pdf
Audio Core Tip 103239-audio.mp3
Conflict-of-Interest Disclosure Form 103239-conflict-of-interest-statement.pdf
Copyright License Agreement 103239-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 103239-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 103239-non-native-speakers.pdf
Peer-review Report 103239-peer-reviews.pdf
Scientific Misconduct Check 103239-scientific-misconduct-check.png
Scientific Editor Work List 103239-scientific-editor-work-list.pdf
CrossCheck Report 103239-crosscheck-report.pdf