ISSN |
2220-315x (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Oncology |
Manuscript Type |
Observational Study |
Article Title |
Environmental mineral density and thyroid malignancy: A multicenter cross-sectional study
|
Manuscript Source |
Unsolicited Manuscript |
All Author List |
John Bukasa-Kakamba, Ayrton I Bangolo, Shruti Wadhwani, Pascal Bayauli, Nikita Wadhwani, Vignesh K Nagesh, Maria J Mou, Princejeet S Chahal, Branly Mbunga, Sindhuja Chindam, Taieba Mushfiq, Abhishek Thapa, Nidhi L Rao, Isis Kapinga Kalambayi, Rahul Y Rajesh, Ipek B Sarioguz, Vishal KR Thoomkuntla, Shamsul Arefin, Navneet Kaur, Manasse Bukasa Mutombo, Satyajeet Singh, Natalia Muto, Surya Vamsi, Pujita Mallampalli, Aliocha Natuhoyila Nkodila, Simcha Weissman and Jean-René M'Buyamba-Kabangu |
ORCID |
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Funding Agency and Grant Number |
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Corresponding Author |
Ayrton I Bangolo, MD, Department of Hematology and Oncology, John Theurer Cancer Center at Hackensack University Medical Center, 92 2nd Street, Hackensack, NJ 07601, United States. ayrtonbangolo@yahoo.com |
Key Words |
Thyroid; Cancer; Nodules; Minerals; Heavy metals |
Core Tip |
Geographical variation in mineral density can potentially impact the prevalence of thyroid malignancies. Our study demonstrated that a higher environmental mineral burden was associated with an increased prevalence of thyroid cancer after adjusting for other covariates. More studies utilizing sophisticated assays to measure serum and environmental levels of various heavy metals could reinforce our study findings. This association holds significant potential in accurate risk-stratification and early detection of thyroid neoplasms amongst patients residing in mineral-laden provinces within the Democratic Republic of Congo. |
Publish Date |
2025-04-16 05:36 |
Citation |
<p>Bukasa-Kakamba J, Bangolo AI, Wadhwani S, Bayauli P, Wadhwani N, Nagesh VK, Mou MJ, Chahal PS, Mbunga B, Chindam S, Mushfiq T, Thapa A, Rao NL, Kalambayi IK, Rajesh RY, Sarioguz IB, Thoomkuntla VK, Arefin S, Kaur N, Mutombo MB, Singh S, Muto N, Vamsi S, Mallampalli P, Nkodila AN, Weissman S, M'Buyamba-Kabangu JR. Environmental mineral density and thyroid malignancy: A multicenter cross-sectional study. <i>World J Exp Med</i> 2025; 15(2): 103371</p> |
URL |
https://www.wjgnet.com/2220-315x/full/v15/i2/103371.htm |
DOI |
https://dx.doi.org/10.5493/wjem.v15.i2.103371 |