Publication Name	World Journal of Gastroenterology
Manuscript ID	103420
Country	Japan

Received	2024-11-19 08:49
Peer-Review Started	2024-11-19 08:50
To Make the First Decision
Return for Revision	2025-01-07 04:15
Revised	2025-01-31 09:35
Second Decision	2025-02-12 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-12 06:30
Articles in Press	2025-02-12 06:30
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-18 01:19
Publish the Manuscript Online	2025-02-26 04:21

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
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Category	Gastroenterology & Hepatology
Manuscript Type	Letter to the Editor
Article Title	Treatment of intermediate-to-advanced unresectable hepatocellular carcinoma is shifting toward a multidisciplinary strategy that includes multiple modalities as needed
Manuscript Source	Invited Manuscript
All Author List	Ken Sato
ORCID	Author(s) ORCID Number Ken Sato http://orcid.org/0000-0002-3202-7983
Funding Agency and Grant Number
Corresponding Author	Ken Sato, Department of Healthcare Informatics, Takasaki University of Health and Welfare, 37-1 Nakaorui-machi, Takasaki 370-0033, Japan. satoken@gunma-u.ac.jp
Key Words	Hepatocellular carcinoma; Molecularly targeted therapy; Immunotherapy; Interventional therapy; Radiation therapy
Core Tip	Many treatment approaches for intermediate-to-advanced unresectable hepatocellular carcinoma are advancing, and there is an increasing amount of evidence regarding the use of combination therapies. Although there may be limitations on combinations in some regions, there is a growing need for research on multimodal treatments, which serve as the cornerstone of personalized medicine. Based on this evidence, we believe that effective combination therapies should be sought for each patient.
Publish Date	2025-02-26 04:21
Citation	<p>Sato K. Treatment of intermediate-to-advanced unresectable hepatocellular carcinoma is shifting toward a multidisciplinary strategy that includes multiple modalities as needed. <i>World J Gastroenterol</i> 2025; 31(10): 103420</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i10/103420.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i10.103420

Full Article (PDF)	WJG-31-103420-with-cover.pdf
Manuscript File	103420_Auto_Edited_074722.docx
Answering Reviewers	103420-answering-reviewers.pdf
Audio Core Tip	103420-audio.mp3
Conflict-of-Interest Disclosure Form	103420-conflict-of-interest-statement.pdf
Copyright License Agreement	103420-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate	103420-non-native-speakers.pdf
Peer-review Report	103420-peer-reviews.pdf
Scientific Misconduct Check	103420-scientific-misconduct-check.png
Scientific Editor Work List	103420-scientific-editor-work-list.pdf
CrossCheck Report	103420-crosscheck-report.pdf