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Articles Published Processes
3/21/2025 6:10:14 AM | Browse: 34 | Download: 54
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Received |
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2024-11-25 09:34 |
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Peer-Review Started |
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2024-11-25 09:34 |
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To Make the First Decision |
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Return for Revision |
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2025-01-10 01:34 |
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Revised |
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2025-01-16 15:24 |
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Second Decision |
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2025-02-12 02:49 |
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Accepted by Journal Editor-in-Chief |
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2025-02-12 13:23 |
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Accepted by Executive Editor-in-Chief |
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2025-02-17 06:01 |
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Articles in Press |
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2025-02-17 06:01 |
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Publication Fee Transferred |
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Edit the Manuscript by Language Editor |
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2025-02-18 14:37 |
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Typeset the Manuscript |
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2025-03-13 09:06 |
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Publish the Manuscript Online |
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2025-03-21 06:10 |
ISSN |
1948-0210 (online) |
Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/ |
Copyright |
© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
Article Reprints |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
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Permissions |
For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
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Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
Website |
http://www.wjgnet.com |
Category |
Cell Biology |
Manuscript Type |
Review |
Article Title |
Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells
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Manuscript Source |
Invited Manuscript |
All Author List |
Yang-Fei Yi, Zi-Qi Fan, Can Liu, Yi-Tong Ding, Yao Chen, Jie Wen, Xiao-Hong Jian and Yu-Fei Li |
ORCID |
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Funding Agency and Grant Number |
Funding Agency |
Grant Number |
National Natural Science Foundation of China |
82072537 |
General Project of Hunan Natural Science Foundation |
2022JJ30412, 2021JJ30464 |
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Corresponding Author |
Jie Wen, Associate Professor, PhD, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, No. 61 West Jiefang Road, Changsha 410013, Hunan Province, China. cashwj@qq.com |
Key Words |
Mesenchymal stem cells; Exosomes; Immunomodulatory effects; Clinical application; Therapeutic potential |
Core Tip |
Exosomes are extracellular vesicles secreted by cells, and they serve as crucial mediators of intercellular communication, playing a pivotal role in the pathogenesis, progression, and therapeutic interventions for various diseases. Given the immense therapeutic potential of exosomes derived from mesenchymal stem cells (MSCs), this review article comprehensively explores their mechanisms underlying immune regulation as well as their therapeutic applications in infection control measures such as tackling tumors or autoimmune diseases among others. This study aims to provide valuable insights into further investigations regarding the mechanism behind MSC-derived exosome actions while offering theoretical references for future clinical utilization of MSC-derived exosomes as cell-free drug preparations. |
Publish Date |
2025-03-21 06:10 |
Citation |
<p>Yi YF, Fan ZQ, Liu C, Ding YT, Chen Y, Wen J, Jian XH, Li YF. Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells. <i>World J Stem Cells</i> 2025; 17(3): 103560</p> |
URL |
https://www.wjgnet.com/1948-0210/full/v17/i3/103560.htm |
DOI |
https://dx.doi.org/10.4252/wjsc.v17.i3.103560 |
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