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3/21/2025 6:10:14 AM | Browse: 34 | Download: 54
Publication Name World Journal of Stem Cells
Manuscript ID 103560
Country China
Received
2024-11-25 09:34
Peer-Review Started
2024-11-25 09:34
To Make the First Decision
Return for Revision
2025-01-10 01:34
Revised
2025-01-16 15:24
Second Decision
2025-02-12 02:49
Accepted by Journal Editor-in-Chief
2025-02-12 13:23
Accepted by Executive Editor-in-Chief
2025-02-17 06:01
Articles in Press
2025-02-17 06:01
Publication Fee Transferred
Edit the Manuscript by Language Editor
2025-02-18 14:37
Typeset the Manuscript
2025-03-13 09:06
Publish the Manuscript Online
2025-03-21 06:10
ISSN 1948-0210 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Cell Biology
Manuscript Type Review
Article Title Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells
Manuscript Source Invited Manuscript
All Author List Yang-Fei Yi, Zi-Qi Fan, Can Liu, Yi-Tong Ding, Yao Chen, Jie Wen, Xiao-Hong Jian and Yu-Fei Li
ORCID
Author(s) ORCID Number
Jie Wen http://orcid.org/0000-0002-5734-4678
Funding Agency and Grant Number
Funding Agency Grant Number
National Natural Science Foundation of China 82072537
General Project of Hunan Natural Science Foundation 2022JJ30412, 2021JJ30464
Corresponding Author Jie Wen, Associate Professor, PhD, Department of Pediatric Orthopedics, Hunan Provincial People’s Hospital, No. 61 West Jiefang Road, Changsha 410013, Hunan Province, China. cashwj@qq.com
Key Words Mesenchymal stem cells; Exosomes; Immunomodulatory effects; Clinical application; Therapeutic potential
Core Tip Exosomes are extracellular vesicles secreted by cells, and they serve as crucial mediators of intercellular communication, playing a pivotal role in the pathogenesis, progression, and therapeutic interventions for various diseases. Given the immense therapeutic potential of exosomes derived from mesenchymal stem cells (MSCs), this review article comprehensively explores their mechanisms underlying immune regulation as well as their therapeutic applications in infection control measures such as tackling tumors or autoimmune diseases among others. This study aims to provide valuable insights into further investigations regarding the mechanism behind MSC-derived exosome actions while offering theoretical references for future clinical utilization of MSC-derived exosomes as cell-free drug preparations.
Publish Date 2025-03-21 06:10
Citation <p>Yi YF, Fan ZQ, Liu C, Ding YT, Chen Y, Wen J, Jian XH, Li YF. Immunomodulatory effects and clinical application of exosomes derived from mesenchymal stem cells. <i>World J Stem Cells</i> 2025; 17(3): 103560</p>
URL https://www.wjgnet.com/1948-0210/full/v17/i3/103560.htm
DOI https://dx.doi.org/10.4252/wjsc.v17.i3.103560
Full Article (PDF) WJSC-17-103560-with-cover.pdf
Manuscript File 103560_Auto_Edited_072113.docx
Answering Reviewers 103560-answering-reviewers.pdf
Audio Core Tip 103560-audio.mp3
Conflict-of-Interest Disclosure Form 103560-conflict-of-interest-statement.pdf
Copyright License Agreement 103560-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s) 103560-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate 103560-non-native-speakers.pdf
Peer-review Report 103560-peer-reviews.pdf
Journal Editor-in-Chief Review Report 103560-journal-editor-in-chief.pdf
Scientific Misconduct Check 103560-scientific-misconduct-check.png
Scientific Editor Work List 103560-scientific-editor-work-list.pdf
CrossCheck Report 103560-crosscheck-report.pdf