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2/27/2025 7:34:10 AM | Browse: 34 | Download: 83
Publication Name World Journal of Clinical Cases
Manuscript ID 103618
Country China
Received
2024-11-26 10:09
Peer-Review Started
2024-11-26 10:10
To Make the First Decision
Return for Revision
2025-01-18 09:59
Revised
2025-01-24 11:30
Second Decision
2025-02-17 02:45
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-17 08:48
Articles in Press
2025-02-17 08:48
Publication Fee Transferred
2025-01-29 03:46
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-02-24 01:00
Publish the Manuscript Online
2025-02-27 07:34
ISSN 2307-8960 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
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Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Medicine, General & Internal
Manuscript Type Case Report
Article Title Refractory Crohn's disease complicated with Guillain-Barré syndrome: A case report
Manuscript Source Unsolicited Manuscript
All Author List A-Niu Liu, Jia-Yi Yang, Xing-Yu Chen, Shan-Shan Wu, Se-Niu Ji Zhi and Shu-Mei Zheng
ORCID
Author(s) ORCID Number
A-Niu Liu http://orcid.org/0009-0004-8997-6356
Jia-Yi Yang http://orcid.org/0000-0002-5282-1092
Xing-Yu Chen http://orcid.org/0009-0001-4251-7804
Shan-Shan Wu http://orcid.org/0009-0001-4215-6690
Se-Niu Ji Zhi http://orcid.org/0009-0003-6008-1631
Shu-Mei Zheng http://orcid.org/0000-0002-4463-9784
Funding Agency and Grant Number
Corresponding Author Shu-Mei Zheng, Chief Physician, MD, Department of Gastroenterology and Hepatology, The General Hospital of Western Theater Command, No. 270 Rongdu Road, Chengdu 610083, Sichuan Province, China. zhengsm@163.com
Key Words Inflammatory bowel disease; Crohn's disease; Ulcerative colitis; Guillain-Barré syndrome; Biological agents; Case report
Core Tip Inflammatory bowel disease (IBD) comprises a group of chronic inflammatory gastrointestinal disorders, including Crohn's disease (CD) and ulcerative colitis. The natural course of IBD can be accompanied by several extraintestinal manifestations. IBD combined with Guillain-Barré syndrome (GBS) has rarely been reported. Here, we describe a patient with refractory CD who stopped responding to multiple drugs and experienced recurrent complicated intestinal fistulas. After several abdominal surgeries and treatment with ustekinumab, he achieved clinical remission. Unfortunately, he developed GBS during maintenance therapy. In patients with IBD combined with GBS, GBS may be a comorbidity, an extraintestinal manifestation of IBD, or an adverse reaction to IBD therapeutic drugs. We suspected that GBS might have been a comorbidity in this patient; therefore, we decided to continue maintenance treatment with ustekinumab along with intravenous immunoglobulin, dexamethasone and traditional Chinese medicine acupuncture, which resulted in a steady improvement in his GBS symptoms and sustained remission of CD.
Publish Date 2025-02-27 07:34
Citation <p>Liu AN, Yang JY, Chen XY, Wu SS, Ji Zhi SN, Zheng SM. Refractory Crohn's disease complicated with Guillain-Barré syndrome: A case report. <i>World J Clin Cases</i> 2025; 13(18): 103618</p>
URL https://www.wjgnet.com/2307-8960/full/v13/i18/103618.htm
DOI https://dx.doi.org/10.12998/wjcc.v13.i18.103618
Full Article (PDF) WJCC-13-103618-with-cover.pdf
CARE Checklist–2016 103618-CARE-Checklist-2016.pdf
Manuscript File 103618_Auto_Edited_083544.docx
Answering Reviewers 103618-answering-reviewers.pdf
Audio Core Tip 103618-audio.mp3
Conflict-of-Interest Disclosure Form 103618-conflict-of-interest-statement.pdf
Copyright License Agreement 103618-copyright-assignment.pdf
Signed Consent for Treatment Form(s) or Document(s) 103618-informed-consent-statement.pdf
Non-Native Speakers of English Editing Certificate 103618-non-native-speakers.pdf
Peer-review Report 103618-peer-reviews.pdf
Scientific Misconduct Check 103618-scientific-misconduct-check.png
Scientific Editor Work List 103618-scientific-editor-work-list.pdf
CrossCheck Report 103618-crosscheck-report.pdf