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1/14/2026 8:39:28 AM | Browse: 24 | Download: 93
Publication Name World Journal of Transplantation
Manuscript ID 103656
Country United Kingdom
Received
2024-11-29 08:13
Peer-Review Started
2024-11-29 08:14
First Decision by Editorial Office Director
2025-03-19 06:53
Return for Revision
2025-03-19 06:53
Revised
2025-07-06 22:03
Publication Fee Transferred
Second Decision by Editor
2025-10-10 02:40
Second Decision by Editor-in-Chief
Final Decision by Editorial Office Director
2025-10-11 04:11
Articles in Press
2025-10-11 04:11
Edit the Manuscript by Language Editor
Typeset the Manuscript
2026-01-07 01:21
Publish the Manuscript Online
2026-01-14 08:39
ISSN 2220-3230 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Transplantation
Manuscript Type Retrospective Cohort Study
Article Title Incidence, risk factors and survival outcomes of post-transplant tertiary hyperparathyroidism in kidney recipients
Manuscript Source Unsolicited Manuscript
All Author List Shmuel Hanson, Jorge Menendez Lorenzo, Chukwuma Austin Chukwu, Anirudh Rao, Rachel Middleton and Philip A Kalra
ORCID
Author(s) ORCID Number
Chukwuma Austin Chukwu http://orcid.org/0000-0002-9488-2256
Philip A Kalra http://orcid.org/0000-0001-7652-1572
Funding Agency and Grant Number
Corresponding Author Chukwuma Austin Chukwu, PhD, Department of Nephrology, Liverpool University Hospitals NHS Foundation Trust, Mount Vernon Street, Liverpool L7 8YE, Mersey Side, United Kingdom. chukwuma.chukwu@rlbuht.nhs.uk
Key Words Post-transplant tertiary hyperparathyroidism; Kidney transplantation; Parathyroid hormone; Parathyroidectomy; Calcimimetics; Graft survival; Risk factors; Mineral bone disorder; Fibroblast growth factor 23; Treatment outcomes
Core Tip This study explores post-transplant tertiary hyperparathyroidism (PT-tHPT) in kidney transplant recipients, identifying elevated pre-transplant calcium and parathyroid hormone levels, prolonged dialysis duration, and acute rejection as key risk factors. PT-tHPT significantly increases the risks of graft loss and patient mortality. However, survival outcomes were comparable across treatment strategies: (1) Conservative management; (2) Calcimimetics; and (3) Parathyroidectomy. These findings highlight the need for optimized pre-transplant care and vigilant post-transplant monitoring to reduce PT-tHPT-related complications. Further research is essential to determine the most effective treatment strategy to improve outcomes and minimize morbidity and mortality associated with PT-tHPT.
Publish Date 2026-01-14 08:39
Citation

Hanson S, Menendez Lorenzo J, Chukwu CA, Rao A, Middleton R, Kalra PA. Incidence, risk factors and survival outcomes of post-transplant tertiary hyperparathyroidism in kidney recipients. World J Transplant 2026; 16(1): 103656

URL https://www.wjgnet.com/2220-3230/full/v16/i1/103656.htm
DOI https://dx.doi.org/10.5500/wjt.v16.i1.103656
Full Article (PDF) WJT-16-103656-with-cover.pdf
STROBE Statement 103656-STROBE-statement.pdf
Manuscript File 103656_Auto_Edited_061057.docx
Answering Reviewers 103656-answering-reviewers.pdf
Audio Core Tip 103656-audio.mp3
Biostatistics Review Certificate 103656-biostatistics-statement.pdf
Conflict-of-Interest Disclosure Form 103656-conflict-of-interest-statement.pdf
Copyright License Agreement 103656-copyright-assignment.pdf
Signed Informed Consent Form(s) or Document(s) 103656-informed-consent-statement.pdf
Institutional Review Board Approval Form or Document 103656-institutional-review-board-statement.pdf
Supplementary Material 103656-supplementary-material.pdf
Peer-review Report 103656-peer-reviews.pdf
Scientific Misconduct Check 103656-scientific-misconduct-check.png
Scientific Editor Work List 103656-scientific-editor-work-list.pdf
CrossCheck Report 103656-crosscheck-report.pdf