Publication Name	World Journal of Gastroenterology
Manuscript ID	103773
Country	China

Received	2024-12-03 12:37
Peer-Review Started	2024-12-03 12:37
To Make the First Decision
Return for Revision	2025-02-14 00:00
Revised	2025-02-23 05:11
Second Decision	2025-04-07 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-04-07 05:06
Articles in Press	2025-04-07 05:06
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-04-14 02:52
Publish the Manuscript Online	2025-04-18 07:43

ISSN	1007-9327 (print) and 2219-2840 (online)
Open Access	Open-Access: This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/Licenses/by-nc/4.0/
Copyright	© The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions	For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher	Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website	http://www.wjgnet.com

Category	Gastroenterology & Hepatology
Manuscript Type	Editorial
Article Title	Delaying liver aging: Analysis of structural and functional alterations
Manuscript Source	Invited Manuscript
All Author List	Yu-Qin Yao, Qiong-Yue Cao and Zheng Li
ORCID	Author(s) ORCID Number Zheng Li http://orcid.org/0000-0002-2882-6600
Funding Agency and Grant Number	Funding Agency Grant Number the National Natural Science Foundation of China 82104525 Open Foundation of Key Laboratory of Tropical Plant Resource Chemistry of Hainan Province rdzw2024s01
Corresponding Author	Zheng Li, PhD, College of Health Sciences, School of Life Sciences, Jiangsu Normal University, No. 101 Shanghai Road, Xuzhou 221000, Jiangsu Province, China. lizhengcpu@163.com
Key Words	Liver aging; Telomere; Hepatocytes; Caloric restriction; Physical exercise; Regeneration
Core Tip	The natural aging process can impair liver functions, including regeneration and metabolism, disrupting hepatic balance and increasing the risk of liver diseases. Cellular and morphological changes are attributable to altered molecular mechanisms. Comprehending the processes of hepatocyte senescence is essential for delaying liver aging through appropriate lifestyle modifications, pinpointing triggers, devising therapeutic strategies, and assessing the effectiveness of interventions against liver diseases. Consequently, it is imperative to conduct further research on the molecular pathways involved.
Publish Date	2025-04-18 07:43
Citation	<p>Yao YQ, Cao QY, Li Z. Delaying liver aging: Analysis of structural and functional alterations. <i>World J Gastroenterol</i> 2025; 31(15): 103773</p>
URL	https://www.wjgnet.com/1007-9327/full/v31/i15/103773.htm
DOI	https://dx.doi.org/10.3748/wjg.v31.i15.103773

Full Article (PDF)	WJG-31-103773-with-cover.pdf
Manuscript File	103773_Auto_Edited_054823.docx
Answering Reviewers	103773-answering-reviewers.pdf
Audio Core Tip	103773-audio.mp3
Conflict-of-Interest Disclosure Form	103773-conflict-of-interest-statement.pdf
Copyright License Agreement	103773-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	103773-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	103773-non-native-speakers.pdf
Peer-review Report	103773-peer-reviews.pdf
Scientific Misconduct Check	103773-scientific-misconduct-check.png
Scientific Editor Work List	103773-scientific-editor-work-list.pdf
CrossCheck Report	103773-crosscheck-report.pdf