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3/26/2025 4:06:53 AM | Browse: 9 | Download: 23
Publication Name World Journal of Hepatology
Manuscript ID 103807
Country India
Received
2024-12-02 14:23
Peer-Review Started
2024-12-02 14:24
To Make the First Decision
Return for Revision
2025-02-08 00:51
Revised
2025-02-16 18:05
Second Decision
2025-02-27 02:40
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief
2025-02-27 10:42
Articles in Press
2025-02-27 10:42
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript
2025-03-07 00:27
Publish the Manuscript Online
2025-03-26 04:06
ISSN 1948-5182 (online)
Open Access This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
Copyright © The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.
Article Reprints For details, please visit: http://www.wjgnet.com/bpg/gerinfo/247
Permissions For details, please visit: http://www.wjgnet.com/bpg/gerinfo/207
Publisher Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
Website http://www.wjgnet.com
Category Gastroenterology & Hepatology
Manuscript Type Minireviews
Article Title Hypochloremia is an underutilised prognostic marker in patients with advanced liver cirrhosis and liver failure
Manuscript Source Invited Manuscript
All Author List Jinit R Soni, Sudheer Marrapu and Ramesh Kumar
ORCID
Author(s) ORCID Number
Jinit R Soni http://orcid.org/0000-0001-5884-0190
Sudheer Marrapu http://orcid.org/0009-0002-8209-8648
Ramesh Kumar http://orcid.org/0000-0001-5136-4865
Funding Agency and Grant Number
Corresponding Author Ramesh Kumar, MD, Department of Gastroenterology, All India Institute of Medical Sciences, Phulwari Sharif, Patna 801507, India. docrameshkr@gmail.com
Key Words Chloride; Hypochloremia; Liver failure; Cirrhosis; Hyponatremia; Prognosis
Core Tip Patients with advanced liver cirrhosis and liver failure frequently experience abnormalities in their serum electrolyte levels. Emerging evidence suggests that serum chloride may provide prognostic information in such patients. Hypochloremia has been associated with higher mortality, worsened liver dysfunction, and a greater need for vasopressors and renal replacement therapy. Despite its prognostic significance, serum chloride is often overshadowed by other electrolytes. Notwithstanding the limited available evidence, we believe that serum chloride is an underutilised prognostic marker in clinical practice. Thus, this article aims to elucidate the prognostic significance of lower serum chloride levels in patients with advanced liver disease.
Publish Date 2025-03-26 04:06
Citation <p>Soni JR, Marrapu S, Kumar R. Hypochloremia is an underutilised prognostic marker in patients with advanced liver cirrhosis and liver failure. <i>World J Hepatol</i> 2025; 17(3): 103807</p>
URL https://www.wjgnet.com/1948-5182/full/v17/i3/103807.htm
DOI https://dx.doi.org/10.4254/wjh.v17.i3.103807
Full Article (PDF) WJH-17-103807-with-cover.pdf
Manuscript File 103807_Auto_Edited_022816.docx
Answering Reviewers 103807-answering-reviewers.pdf
Audio Core Tip 103807-audio.mp3
Conflict-of-Interest Disclosure Form 103807-conflict-of-interest-statement.pdf
Copyright License Agreement 103807-copyright-assignment.pdf
Non-Native Speakers of English Editing Certificate 103807-non-native-speakers.pdf
Peer-review Report 103807-peer-reviews.pdf
Scientific Misconduct Check 103807-scientific-misconduct-check.png
Scientific Editor Work List 103807-scientific-editor-work-list.pdf
CrossCheck Report 103807-crosscheck-report.pdf