Publication Name	World Journal of Hepatology
Manuscript ID	103854
Country	China

Received	2024-12-12 14:58
Peer-Review Started	2024-12-23 03:51
To Make the First Decision
Return for Revision	2025-01-10 03:34
Revised	2025-01-17 08:07
Second Decision	2025-02-11 02:39
Accepted by Journal Editor-in-Chief
Accepted by Executive Editor-in-Chief	2025-02-12 10:20
Articles in Press	2025-02-12 10:20
Publication Fee Transferred
Edit the Manuscript by Language Editor
Typeset the Manuscript	2025-02-20 01:36
Publish the Manuscript Online	2025-03-26 04:06

ISSN	1948-5182 (online)
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Category	Gastroenterology & Hepatology
Manuscript Type	Minireviews
Article Title	Gut microbiota differences, metabolite changes, and disease intervention during metabolic - dysfunction - related fatty liver progression
Manuscript Source	Invited Manuscript
All Author List	Jian-Zhong Shu, Yu-Han Huang, Xiao-Hong He, Feng-Ying Liu, Qian-Qian Liang, Xue-Tong Yong and Yong-Fang Xie
ORCID	Author(s) ORCID Number Jian-Zhong Shu http://orcid.org/0009-0000-8412-8834 Yu-Han Huang http://orcid.org/0009-0000-2222-2796 Feng-Ying Liu http://orcid.org/0009-0006-0788-8649 Qian-Qian Liang http://orcid.org/0009-0007-8118-1083 Xue-Tong Yong http://orcid.org/0009-0003-0431-2503 Yong-Fang Xie http://orcid.org/0000-0002-8210-5732
Funding Agency and Grant Number	Funding Agency Grant Number Natural Science Foundation of Chongqing cstc2021jcyj-msxmx0848 Chongqing Bishan Scientific Research Project BSKJ2022006 National Natural Science Foundation of China 81773954 National College Students Innovation and Entrepreneurship Program 202310617015
Corresponding Author	Yong-Fang Xie, PhD, Professor, School of Life Health Information Science and Engineering, Chongqing University of Posts and Telecommunications, detailed address, Chongqing 400065, China. xieyf@cqupt.edu.cn
Key Words	Metabolic dysfunction-associated steatotic liver disease; Gut microbiota; Short-chain fatty acids; Bile acids; Lipopolysaccharides; Probiotics
Core Tip	This review elaborates in detail on the comparison of the gut microbiota between metabolic dysfunction-associated steatotic liver disease patients and healthy individuals, between metabolic dysfunction-associated fatty liver and metabolic dysfunction-associated steatohepatitis, as well as between the stages of mild fibrosis and significant fibrosis. It reveals the changes in the production and action mechanisms of short-chain fatty acids, bile acids, and lipopolysaccharides brought about by the changes in the gut microbiota. In addition, it also explores the regulation of the gut microbiota in the disease by using probiotics and the production and inhibition of related disease factors.
Publish Date	2025-03-26 04:06
Citation	<p>Shu JZ, Huang YH, He XH, Liu FY, Liang QQ, Yong XT, Xie YF. Gut microbiota differences, metabolite changes, and disease intervention during metabolic - dysfunction - related fatty liver progression. <i>World J Hepatol</i> 2025; 17(3): 103854</p>
URL	https://www.wjgnet.com/1948-5182/full/v17/i3/103854.htm
DOI	https://dx.doi.org/10.4254/wjh.v17.i3.103854

Full Article (PDF)	WJH-17-103854-with-cover.pdf
Manuscript File	103854_Auto_Edited_055553.docx
Answering Reviewers	103854-answering-reviewers.pdf
Audio Core Tip	103854-audio.mp3
Conflict-of-Interest Disclosure Form	103854-conflict-of-interest-statement.pdf
Copyright License Agreement	103854-copyright-assignment.pdf
Approved Grant Application Form(s) or Funding Agency Copy of any Approval Document(s)	103854-foundation-statement.pdf
Non-Native Speakers of English Editing Certificate	103854-non-native-speakers.pdf
Peer-review Report	103854-peer-reviews.pdf
Scientific Misconduct Check	103854-scientific-misconduct-check.png
Scientific Editor Work List	103854-scientific-editor-work-list.pdf
CrossCheck Report	103854-crosscheck-report.pdf