| ISSN |
1949-8462 (online) |
| Open Access |
This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/ |
| Copyright |
The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved. |
| Article Reprints |
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| Permissions |
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| Publisher |
Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA |
| Website |
http://www.wjgnet.com |
| Category |
Cardiac & Cardiovascular Systems |
| Manuscript Type |
Minireviews |
| Article Title |
Role of interleukins in the pathogenesis of coronary heart disease: A literature review
|
| Manuscript Source |
Invited Manuscript |
| All Author List |
Saira Rafaqat, Azeem Azam, Ramsha Hafeez, Hamza Faseeh, Maria Tariq, Muhammad Asif, Amber Arshad and Iqra Noshair |
| ORCID |
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| Funding Agency and Grant Number |
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| Corresponding Author |
Saira Rafaqat, PhD, Department of Zoology, Lahore College for Women University, Jail Rd, Near Wapda Flats, Lahore 54000, Pakistan. saera.rafaqat@gmail.com |
| Key Words |
Coronary heart disease; Interleukins; Inflammation; Pathogenesis |
| Core Tip |
Many studies have reported cytokines cause the pathogenesis of coronary heart disease (CHD). Interleukin (IL) are integral to the pathogenesis of CHD, through their roles in promoting inflammation, endothelial dysfunction, plaque formation, and thrombosis. The review aims to report the role of IL such as IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, IL-7, IL-8, IL-9, and IL-10 in the pathogenesis of CHD, therapeutic strategies, identify knowledge gaps and highlight future research directions to improve the understanding and management of CHD. |
| Publish Date |
2025-03-21 07:11 |
| Citation |
<p>Rafaqat S, Azam A, Hafeez R, Faseeh H, Tariq M, Asif M, Arshad A, Noshair I. Role of interleukins in the pathogenesis of coronary heart disease: A literature review. <i>World J Cardiol</i> 2025; 17(3): 103947</p> |
| URL |
https://www.wjgnet.com/1949-8462/full/v17/i3/103947.htm |
| DOI |
https://dx.doi.org/10.4330/wjc.v17.i3.103947 |
